Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MITF | O75030 | 3/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 3/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.38 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8021117 | 0.94 | BDKRB2 (0.39) | BDKRB2NPC1RAB9ASMN1; SMN2MITF | |
| SCHEMBL8020616 | 0.93 | CASR (0.42) | BDKRB2NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL8036739 | 0.93 | NPC1 (0.42) | BDKRB2NPC1RAB9ASMN1; SMN2MITF | |
| SCHEMBL8020975 | 0.90 | BDKRB2 (0.41) | BDKRB2NPC1RAB9ASMN1; SMN2MITF | |
| SCHEMBL8030429 | 0.90 | NPC1 (0.40) | BDKRB2NPC1RAB9ASMN1; SMN2MITF | |
| SCHEMBL8030021 | 0.90 | KMT2A (0.35) | SMN1; SMN2MAPTCASRCXCR1CXCR2 | |
| SCHEMBL8020575 | 0.90 | CASR (0.35) | CASRCXCR1CXCR2 | |
| SCHEMBL8030193 | 0.88 | SMN1; SMN2 (0.33) | BDKRB2RAB9ASMN1; SMN2MAPTCASR | |
| SCHEMBL8029973 | 0.88 | BDKRB2 (0.40) | BDKRB2NPC1RAB9ASMN1; SMN2MITF | |
| SCHEMBL8033877 | 0.88 | MEN1 (0.33) | BDKRB2SMN1; SMN2NR1H4CXCR1CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985660-A1 | AMINOPHENOL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-03-15 | — | — | EP | disclosed |
| CN-1178523-A | Aminophenol derivatives | DIICHI PHARMACEUTICAL CO LTD (JP) | 1998-04-08 | — | — | CN | disclosed |