Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 4/20 | 0.78 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.78 |
| ▸ | NR3C1 | P04150 | 13/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.76 |
| ▸ | AR | P10275 | 2/20 | 0.76 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.76 |
| ▸ | TNF | P01375 | 1/20 | 0.76 |
| ▸ | IL6 | P05231 | 1/20 | 0.76 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.76 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.76 |
| ▸ | GLUL | P15104 | 1/20 | 0.76 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.76 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.76 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.76 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | F2 | P00734 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3214128 | 1.00 | PGR (0.78) | PGRHIF1ANR3C1HSD17B10CYP3A4 | |
| SCHEMBL8020748 | 1.00 | PGR (0.78) | PGRHIF1ANR3C1HSD17B10CYP3A4 | |
| SCHEMBL5524342 | 0.93 | PGR (0.78) | PGRHIF1ANR3C1HSD17B10CYP3A4 | |
| SCHEMBL13596192 | 0.89 | PGR (0.83) | PGRHIF1ANR3C1HSD17B10CYP3A4 | |
| SCHEMBL13368125 | 0.89 | PGR (0.83) | PGRHIF1ANR3C1HSD17B10CYP3A4 | |
| SCHEMBL9069792 | 0.89 | HIF1A (0.71) | PGRHIF1ANR3C1HSD17B10CYP3A4 | |
| SCHEMBL15662128 | 0.88 | PGR (0.78) | PGRHIF1ANR3C1HSD17B10CYP3A4 | |
| SCHEMBL23633793 | 0.88 | PGR (0.81) | PGRHIF1ANR3C1HSD17B10CYP3A4 | |
| Prednisolone Acetate SCHEMBL10118889 | 0.88 | HIF1A (1.00) | PGRHIF1ANR3C1HSD17B10CYP3A4 | |
| Prednisolone Acetate SCHEMBL13044467 | 0.88 | HIF1A (1.00) | PGRHIF1ANR3C1HSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763054-B1 | PROCESS FOR PREPARING DELTA 9,11 AND 21-CHLORO CORTICOSTEROIDS | SCHERING CORP (US) | 2000-01-05 | — | — | EP | disclosed |
| US-5750745-A | STEROIDS | SCHERING CORPORATION (US) | 1998-05-12 | — | — | US | disclosed |