SCHEMBL5524342

SCHEMBL5524342

C[C@]12C=CC(=O)C=C1CC[C@@H]1[C@@H]2C(O)C[C@@]2(C)[C@H]1CC[C@]2(O)C(=O)COS(=O)(=O)O

nearest known ligand 0.78

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ PGR P06401 4/20 0.78
▸ HIF1A Q16665 3/20 0.78
▸ NR3C1 P04150 13/20 0.76
▸ HSD17B10 Q99714 2/20 0.76
▸ CYP3A4 P08684 2/20 0.76
▸ AR P10275 2/20 0.76
▸ ABCB11 O95342 1/20 0.76
▸ TNF P01375 1/20 0.76
▸ IL6 P05231 1/20 0.76
▸ SERPINA6 P08185 1/20 0.76
▸ NR3C2 P08235 1/20 0.76
▸ GLUL P15104 1/20 0.76
▸ ADAM17 P78536 1/20 0.76
▸ GPBAR1 Q8TDU6 1/20 0.76
▸ CYP2C19 P33261 1/20 0.76
▸ LMNA P02545 1/20 0.70
▸ KMT2A Q03164 1/20 0.59
▸ F2 P00734 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8020744 0.93 PGR (0.78) PGRHIF1ANR3C1HSD17B10CYP3A4
SCHEMBL3214128 0.93 PGR (0.78) PGRHIF1ANR3C1HSD17B10CYP3A4
SCHEMBL8020748 0.93 PGR (0.78) PGRHIF1ANR3C1HSD17B10CYP3A4
SCHEMBL13596192 0.89 PGR (0.83) PGRHIF1ANR3C1HSD17B10CYP3A4
SCHEMBL13368125 0.89 PGR (0.83) PGRHIF1ANR3C1HSD17B10CYP3A4
SCHEMBL9069792 0.89 HIF1A (0.71) PGRHIF1ANR3C1HSD17B10CYP3A4
Prednisolone SCHEMBL5524347 0.89 NR3C1 (0.93) PGRHIF1ANR3C1HSD17B10CYP3A4
SCHEMBL23633793 0.88 PGR (0.81) PGRHIF1ANR3C1HSD17B10CYP3A4
Prednisolone Acetate SCHEMBL8000 0.88 HIF1A (1.00) PGRHIF1ANR3C1HSD17B10CYP3A4
Prednisolone Acetate SCHEMBL13044467 0.88 HIF1A (1.00) PGRHIF1ANR3C1HSD17B10CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5650170-A Dosage form for delivering drug at a controlled rate to the intestine and to the colon ALZA CORPORATION (US) 1997-07-22 — — US claimed
US-20240423907-A1 Improved Nasal Administration of Pharmaceutical Formulations CYRANO THERAPEUTICS, INC. 2024-12-26 — — US disclosed
CN-119113101-A Methods of treating diffuse large B-cell lymphomas using anti-CD 79B immunoconjugates 基因泰克公司 2024-12-13 — — CN disclosed
CN-119012999-A Improved nasal administration of pharmaceutical formulations 思瑞诺医疗有限公司 2024-11-22 — — CN disclosed
EP-4460284-A1 IMPROVED NASAL ADMINISTRATION OF PHARMACEUTICAL FORMULATIONS Cyrano Therapeutics, Inc. (US) 2024-11-13 — — EP disclosed
US-20240336697-A1 METHODS OF USING ANTI-CD79B IMMUNOCONJUGATES TO TREAT DIFFUSE LARGE B-CELL LYMPHOMA GENENTECH, INC. (US) 2024-10-10 — — US disclosed
CN-118355029-A Methods of treating diffuse large B-cell lymphomas using anti-CD 79B immunoconjugates 基因泰克公司 2024-07-16 — — CN disclosed
EP-4380978-A1 METHODS OF USING ANTI-CD79B IMMUNOCONJUGATES TO TREAT DIFFUSE LARGE B-CELL LYMPHOMA Genentech, Inc. (US) 2024-06-12 — — EP disclosed
WO-2023133460-A1 IMPROVED NASAL ADMINISTRATION OF PHARMACEUTICAL FORMULATIONS CYRANO THERAPEUTICS, INC. (US) 2023-07-13 — — WO disclosed
CN-115996703-A Compositions and methods for treating ocular disorders by contact lens mediated drug delivery 奇奥拉制药股份有限公司 2023-04-21 — — CN disclosed
EP-0546038-B1 DOSAGE FORM FOR TIME-VARYING PATTERNS OF DRUG DELIVERY ALZA CORP (US) 1994-07-27 — — EP disclosed
EP-0521074-B1 DOSAGE FORM FOR DELIVERING DRUG TO THE INTESTINE ALZA CORP (US) 1994-03-02 — — EP disclosed
US-5232705-A Hypotensive agents. vasodilators ALZA CORPORATION (US) 1993-08-03 — — US disclosed
EP-0546038-A1 DOSAGE FORM FOR TIME-VARYING PATTERNS OF DRUG DELIVERY. ALZA CORP (US) 1993-06-16 — — EP disclosed
US-5178866-A DOSAGE FORM FOR DELIVERING DRUG TO THE INTESTINE ALZA CORPORATION (US) 1993-01-12 — — US disclosed
EP-0521074-A1 DOSAGE FORM FOR DELIVERING DRUG TO THE INTESTINE. ALZA CORP (US) 1993-01-07 — — EP disclosed
US-5156850-A DOSAGE FORM FOR TIME-VARYING PATTERNS OF DRUG DELIVERY ALZA CORPORATION (US) 1992-10-20 — — US disclosed
WO-1992004011-A1 DOSAGE FORM FOR TIME-VARYING PATTERNS OF DRUG DELIVERY ALZA CORPORATION (US) 1992-03-19 — — WO disclosed
WO-1991014426-A1 DOSAGE FORM FOR DELIVERING DRUG TO THE INTESTINE ALZA CORPORATION (US) 1991-10-03 — — WO disclosed
US-4904474-A Delivery of drug to colon by oral disage form ALZA CORPORATION (US) 1990-02-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240336697-A1 METHODS OF USING ANTI-CD79B IMMUNOCONJUGATES TO TREAT DIFFUSE LARGE B-CELL LYMPHOMA CD79B, CD99, BCL6 PGR 1742/4885HIF1A 4135/4885NR3C1 624/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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