Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | PPIB | P23284 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8030634 | 0.94 | KMT2A (0.36) | KMT2AMEN1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL8020736 | 0.93 | ITGB1 (0.36) | KMT2AMEN1MAPK1SMN1; SMN2PDE5A | |
| SCHEMBL8031875 | 0.92 | MAPK1 (0.40) | KMT2AMEN1MAPK1SMN1; SMN2PPARD | |
| SCHEMBL8030646 | 0.91 | KMT2A (0.36) | KMT2AMEN1MAPK1SMN1; SMN2PDE5A | |
| SCHEMBL8031868 | 0.90 | PPIB (0.38) | KMT2AMEN1MAPK1SMN1; SMN2PPARD | |
| SCHEMBL8020901 | 0.90 | SMN1; SMN2 (0.37) | KMT2AMEN1MAPK1SMN1; SMN2PDE5A | |
| SCHEMBL8029977 | 0.90 | KMT2A (0.38) | KMT2AMEN1MAPK1SMN1; SMN2NPC1 | |
| SCHEMBL8020628 | 0.88 | KMT2A (0.42) | KMT2AMEN1SMN1; SMN2PPARDLMNA | |
| SCHEMBL8029961 | 0.88 | KMT2A (0.38) | KMT2AMEN1MAPK1SMN1; SMN2PPARD | |
| SCHEMBL8020589 | 0.88 | SMN1; SMN2 (0.35) | KMT2AMEN1MAPK1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985660-A1 | AMINOPHENOL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-03-15 | — | — | EP | disclosed |