Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | BDKRB2 | P30411 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PPIB | P23284 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8020758 | 0.94 | KMT2A (0.37) | KMT2AMEN1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL8020589 | 0.94 | SMN1; SMN2 (0.35) | KMT2AMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL8033942 | 0.92 | KMT2A (0.40) | KMT2AMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL8031924 | 0.91 | KMT2A (0.35) | KMT2AMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL8036207 | 0.91 | GRM5 (0.38) | KMT2AMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL8029983 | 0.91 | SMN1; SMN2 (0.36) | KMT2AMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL8030447 | 0.90 | KMT2A (0.37) | KMT2AMEN1MAPK1SMN1; SMN2BDKRB2 | |
| SCHEMBL8030465 | 0.89 | KMT2A (0.38) | KMT2AMEN1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL8020736 | 0.88 | ITGB1 (0.36) | KMT2AMEN1MAPK1SMN1; SMN2NPC1 | |
| SCHEMBL8020564 | 0.87 | KDM4E (0.37) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985660-A1 | AMINOPHENOL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-03-15 | — | — | EP | disclosed |