SCHEMBL8020759

SCHEMBL8020759

Nc1cc(OS(=O)(=O)O)cc(OS(=O)(=O)O)c1O

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CISD1 Q9NZ45 1/20 0.41
F10 P00742 5/20 0.36
GAA P10253 2/20 0.33
GLA P06280 1/20 0.33
ALDH1A1 P00352 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TYR P14679 1/20 0.32
SLC22A6 Q4U2R8 1/20 0.32
NSD2 O96028 1/20 0.32
PLCG1 P19174 1/20 0.32
DNMT1 P26358 1/20 0.32
CASP6 P55212 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CA5A P35218 1/20 0.31
CYP1A2 P05177 1/20 0.31
NT5E P21589 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9224372 0.84 CISD1 (0.47) CISD1F10GAAGLATYR
SCHEMBL1389341 0.80 CYP1A2 (0.46) CISD1F10GAAGLATYR
SCHEMBL8018809 0.79 CISD1 (0.40) CISD1GAAGLAALDH1A1HSD17B10
SCHEMBL10709141 0.79 KDM4E (0.48) CISD1GAAGLAALDH1A1HSD17B10
SCHEMBL8018538 0.79 CA1 (0.38) GAAALDH1A1HSD17B10SLC22A6NSD2
SCHEMBL7755552 0.77 GLA (0.44) CISD1F10GAAGLAALDH1A1
SCHEMBL11028747 0.77 GAA (0.47) CISD1F10GAAGLAALDH1A1
SCHEMBL8997103 0.74 PKM (0.41) CISD1F10GAAGLAALDH1A1
SCHEMBL10783777 0.74 F10 (0.37) CISD1F10GAAGLASLC22A6
SCHEMBL10606946 0.74 CISD1 (0.36) CISD1F10GAAGLASLC22A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648816-B1 Dyeing of leather with dyestuff mixtures CIBA SC HOLDING AG (CH) 2000-01-26 EP disclosed
EP-0648816-A1 Dyeing of leather with dyestuff mixtures CIBA-GEIGY AG (CH) 1995-04-19 EP disclosed
EP-0231147-B1 PROCESS FOR THE TRICHROMATIC DYEING OF LEATHER CIBA-GEIGY AG (CH) 1992-01-15 EP disclosed
EP-0357554-A2 Complex metal compounds CIBA-GEIGY AG (CH) 1990-03-07 EP disclosed
EP-0181836-B1 PROCESS FOR IMPROVING THE LIGHT FASTNESS OF DYED LEATHERS CIBA-GEIGY AG (CH) 1988-12-21 EP disclosed
EP-0148120-B1 ASYMMETRICAL 1:2 CHROMIUM COMPLEX DYES CIBA-GEIGY AG (CH) 1988-11-23 EP disclosed
EP-0148121-B1 ASYMMETRICAL 1:2 CHROMIUM COMPLEX DYES CIBA-GEIGY AG (CH) 1988-11-09 EP disclosed
EP-0150676-B1 1:2 CHROMIUM COMPLEX DYES CIBA-GEIGY AG (CH) 1988-10-12 EP disclosed
EP-0151369-B1 ASYMMETRICAL 1:2 CHROME COMPLEXES CONTAINING AN AZO COMPOUND AND AN AZOMETHINE COMPOUND CIBA-GEIGY AG (CH) 1987-09-09 EP disclosed
EP-0231147-A2 Process for the trichromatic dyeing of leather CIBA-GEIGY AG (CH) 1987-08-05 EP disclosed
EP-0019851-B1 1:2 CHROMIUM COMPLEX DYESTUFFS OF THE AZOMETHINE AND/OR AZO SERIES, THEIR PREPARATION AND USE IN DYEING AND PRINTING POLYAMIDE OR CELLULOSE MATERIALS CIBA-GEIGY AG (CH) 1983-05-11 EP disclosed
EP-0068245-A1 Dyestuffs containing sulphonic acid groups BASF Aktiengesellschaft (DE) 1983-01-05 EP disclosed
EP-0061670-A1 Process for dyeing leather and pelts with dye mixtures CIBA-GEIGY AG (CH) 1982-10-06 EP disclosed
EP-0009466-B1 1 : 2-BIS-CHROMIUM-COMPLEX DYESTUFFS FROM POLYAZO- OR DISAZO-AZOMETHINE COMPOUNDS, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1982-05-19 EP disclosed
EP-0048693-A2 Disazo dyestuffs, metal complexes thereof, their preparation and use CIBA-GEIGY AG (CH) 1982-03-31 EP disclosed
EP-0005207-B1 BIS-1:2 CHROME-DISAZO-BISAZO METHINE DYESTUFFS, THEIR PREPARATION AND USE FOR DYEING OF LEATHER CIBA-GEIGY AG (CH) 1981-12-09 EP disclosed
EP-0037377-A1 Metal-complex dyestuffs, their preparation and use CIBA-GEIGY AG (CH) 1981-10-07 EP disclosed
EP-0019851-A1 1:2 Chromium complex dyestuffs of the azomethine and/or azo series, their preparation and use in dyeing and printing polyamide or cellulose materials CIBA-GEIGY AG (CH) 1980-12-10 EP disclosed
EP-0009466-A1 1 : 2-Bis-chromium-complex dyestuffs from polyazo- or disazo-azomethine compounds, their preparation and their use CIBA-GEIGY AG (CH) 1980-04-02 EP disclosed
EP-0005207-A2 Bis-1:2 chrome-disazo-bisazo methine dyestuffs, their preparation and use for dyeing of leather CIBA-GEIGY AG (CH) 1979-11-14 EP disclosed