Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 5/20 | 0.38 |
| ▸ | CA2 | P00918 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 3/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8020759 | 0.79 | CISD1 (0.41) | CISD1ALDH1A1HSD17B10GAAGLA | |
| SCHEMBL11353322 | 0.78 | CYP3A4 (0.56) | CISD1ALDH1A1HSD17B10THRBALOX15 | |
| SCHEMBL10709141 | 0.78 | KDM4E (0.48) | CISD1ALDH1A1HSD17B10THRBCYP3A4 | |
| SCHEMBL7755535 | 0.73 | NSD2 (0.59) | ALDH1A1HSD17B10ALOX15CYP3A4RECQL | |
| SCHEMBL9053013 | 0.72 | CISD1 (0.50) | CISD1TSHRCA1CA2GAA | |
| SCHEMBL10448617 | 0.72 | ALDH1A1 (0.53) | CISD1ALDH1A1HSD17B10THRBALOX15 | |
| SCHEMBL7625960 | 0.71 | NT5E (0.53) | CISD1ALDH1A1HSD17B10THRBRECQL | |
| SCHEMBL14015364 | 0.71 | CISD1 (0.43) | CISD1ALDH1A1TSHRCA1CA2 | |
| SCHEMBL6935562 | 0.71 | CASP6 (0.53) | ALDH1A1HSD17B10THRBALOX15CYP3A4 | |
| SCHEMBL10900544 | 0.71 | NR4A1 (0.52) | CISD1ALDH1A1HSD17B10THRBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648816-B1 | Dyeing of leather with dyestuff mixtures | CIBA SC HOLDING AG (CH) | 2000-01-26 | — | — | EP | disclosed |
| EP-0648816-A1 | Dyeing of leather with dyestuff mixtures | CIBA-GEIGY AG (CH) | 1995-04-19 | — | — | EP | disclosed |
| EP-0061670-B2 | Process for dyeing leather and pelts with dye mixtures | CIBA GEIGY AG (CH) | 1994-06-01 | — | — | EP | disclosed |
| EP-0231147-B1 | PROCESS FOR THE TRICHROMATIC DYEING OF LEATHER | CIBA-GEIGY AG (CH) | 1992-01-15 | — | — | EP | disclosed |
| EP-0181836-B1 | PROCESS FOR IMPROVING THE LIGHT FASTNESS OF DYED LEATHERS | CIBA-GEIGY AG (CH) | 1988-12-21 | — | — | EP | disclosed |
| EP-0148120-B1 | ASYMMETRICAL 1:2 CHROMIUM COMPLEX DYES | CIBA-GEIGY AG (CH) | 1988-11-23 | — | — | EP | disclosed |
| EP-0148121-B1 | ASYMMETRICAL 1:2 CHROMIUM COMPLEX DYES | CIBA-GEIGY AG (CH) | 1988-11-09 | — | — | EP | disclosed |
| EP-0150676-B1 | 1:2 CHROMIUM COMPLEX DYES | CIBA-GEIGY AG (CH) | 1988-10-12 | — | — | EP | disclosed |
| EP-0231147-A2 | Process for the trichromatic dyeing of leather | CIBA-GEIGY AG (CH) | 1987-08-05 | — | — | EP | disclosed |
| EP-0110825-B1 | ASYMMETRICAL 1:2 CHROMIUM COMPLEX DYESTUFFS CONTAINING ONE AZO AND ONE AZOMETHINE COMPOUND | CIBA-GEIGY AG (CH) | 1987-04-08 | — | — | EP | disclosed |
| EP-0181836-A1 | Process for improving the light fastness of dyed leathers | CIBA-GEIGY AG (CH) | 1986-05-21 | — | — | EP | disclosed |
| EP-0048693-B1 | DISAZO DYESTUFFS, METAL COMPLEXES THEREOF, THEIR PREPARATION AND USE | CIBA-GEIGY AG (CH) | 1986-01-08 | — | — | EP | disclosed |
| EP-0150676-A2 | 1:2 Chromium complex dyes | CIBA-GEIGY AG (CH) | 1985-08-07 | — | — | EP | disclosed |
| EP-0061670-B1 | PROCESS FOR DYEING LEATHER AND PELTS WITH DYE MIXTURES | CIBA-GEIGY AG (CH) | 1985-06-12 | — | — | EP | disclosed |
| EP-0027950-B1 | FIBRE-REACTIVE CHROMIUM COMPLEX DYESTUFFS, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1984-02-15 | — | — | EP | disclosed |
| EP-0082117-A1 | Chromium complexes of polyazo dyestuffs | CIBA-GEIGY AG (CH) | 1983-06-22 | — | — | EP | disclosed |
| EP-0061670-A1 | Process for dyeing leather and pelts with dye mixtures | CIBA-GEIGY AG (CH) | 1982-10-06 | — | — | EP | disclosed |
| EP-0048693-A2 | Disazo dyestuffs, metal complexes thereof, their preparation and use | CIBA-GEIGY AG (CH) | 1982-03-31 | — | — | EP | disclosed |
| EP-0027950-A2 | Fibre-reactive chromium complex dyestuffs, their preparation and their use | CIBA-GEIGY AG (CH) | 1981-05-06 | — | — | EP | disclosed |
| EP-0009466-A1 | 1 : 2-Bis-chromium-complex dyestuffs from polyazo- or disazo-azomethine compounds, their preparation and their use | CIBA-GEIGY AG (CH) | 1980-04-02 | — | — | EP | disclosed |