Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | PPM1B | O75688 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8018907 | 0.89 | NPSR1 (0.35) | SLC1A2SLC1A1NPSR1MAPT | |
| SCHEMBL8008305 | 0.87 | MAPT (0.40) | SLC1A2SLC1A1NPSR1MAPTCYP2C19 | |
| SCHEMBL8018805 | 0.80 | APLNR (0.32) | NPSR1CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL8452132 | 0.77 | SLC1A2 (0.38) | SLC1A2SLC1A1CYP1A2CYP2C9TSHR | |
| SCHEMBL7104310 | 0.72 | ALDH1A1 (0.50) | SLC1A2SLC1A1NPSR1MAPTCYP1A2 | |
| SCHEMBL7104313 | 0.72 | ALDH1A1 (0.50) | SLC1A2SLC1A1NPSR1MAPTCYP1A2 | |
| SCHEMBL12494007 | 0.72 | ALDH1A1 (0.50) | SLC1A2SLC1A1NPSR1MAPTCYP1A2 | |
| SCHEMBL987271 | 0.72 | ALDH1A1 (0.50) | SLC1A2SLC1A1NPSR1MAPTCYP1A2 | |
| SCHEMBL30771654 | 0.67 | ALDH1A1 (0.45) | SLC1A2SLC1A1NPSR1CYP1A2CYP2C9 | |
| SCHEMBL23925613 | 0.67 | SLC1A2 (0.41) | SLC1A2SLC1A1CYP1A2CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973720-A1 | 2-SUBSTITUTED BENZOYL-CYCLOALKYL-1-CARBOXYLIC ACID DERIVATIVES | PHARMACIA & UPJOHN S.p.A. (IT) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998040344-A1 | 2-SUBSTITUTED BENZOYL-CYCLOALKYL-1-CARBOXYLIC ACID DERIVATIVES | PHARMACIA & UPJOHN S.P.A. (IT) | 1998-09-17 | — | — | WO | disclosed |