Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8008305 | 0.95 | MAPT (0.40) | NPSR1MAPTSLC1A2SLC1A1BTK | |
| SCHEMBL8020908 | 0.89 | SLC1A2 (0.37) | NPSR1MAPTSLC1A2SLC1A1 | |
| SCHEMBL9006136 | 0.79 | GRM4 (0.35) | SLC1A2SLC1A1 | |
| SCHEMBL8018805 | 0.77 | APLNR (0.32) | NPSR1 | |
| SCHEMBL30165614 | 0.75 | CYP4F2 (0.37) | NPSR1MAPTSLC1A2SLC1A1CYP4F2 | |
| SCHEMBL895754 | 0.73 | GRM4 (0.34) | SLC1A2SLC1A1 | |
| SCHEMBL6916576 | 0.71 | MAPT (0.41) | NPSR1MAPTSLC1A2SLC1A1CYP4F2 | |
| SCHEMBL8970157 | 0.67 | CYP1A2 (0.30) | — | |
| SCHEMBL8970085 | 0.67 | CYP1A2 (0.30) | — | |
| SCHEMBL17895908 | 0.67 | GRM2 (0.41) | NPSR1MAPTBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973720-A1 | 2-SUBSTITUTED BENZOYL-CYCLOALKYL-1-CARBOXYLIC ACID DERIVATIVES | PHARMACIA & UPJOHN S.p.A. (IT) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998040344-A1 | 2-SUBSTITUTED BENZOYL-CYCLOALKYL-1-CARBOXYLIC ACID DERIVATIVES | PHARMACIA & UPJOHN S.P.A. (IT) | 1998-09-17 | — | — | WO | disclosed |