Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8020675 | 0.76 | TDP1 (0.42) | KDM4EMAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL8021822 | 0.75 | PARP1 (0.45) | KDM4EMAPTGAAALDH1A1POLB | |
| SCHEMBL8021983 | 0.73 | CYP3A4 (0.32) | MAPTTSHRCYP3A4CYP2C19CYP2D6 | |
| SCHEMBL8815713 | 0.68 | TSHR (0.34) | ALDH1A1TSHRCYP3A4CYP2C19CYP2D6 | |
| SCHEMBL514887 | 0.68 | KDM4E (0.60) | KDM4EGAAL3MBTL1TSHRPARP1 | |
| SCHEMBL23320362 | 0.67 | PTGDR2 (0.56) | KDM4EMAPTALDH1A1POLBCYP2C19 | |
| SCHEMBL241785 | 0.66 | PARP1 (0.68) | MAPTGAAALDH1A1RAB9ANPC1 | |
| SCHEMBL30153175 | 0.66 | PARP1 (0.68) | MAPTGAAALDH1A1RAB9ANPC1 | |
| SCHEMBL7626205 | 0.66 | RXFP1 (0.51) | KDM4EMAPTGAAALDH1A1POLB | |
| SCHEMBL25308751 | 0.65 | CYP1A2 (0.71) | MAPTGAAALDH1A1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6140282-A | LUBRICATING BASE OIL AND A MINOR AMOUNT OF A MIXTURE OF HIGH TOTAL BASE NUMBER(TBN), MEDIUM TBN AND LOW/NEUTRAL TBN DETERGENTS WHEREIN METAL SALICYLATE DETERGENT IS AT LEAST ONE OF THE MEDIUM OR LOW/NEUTRAL TBN DETERGENTS | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2000-10-31 | — | — | US | disclosed |
| EP-0802187-B1 | Hydroxypyridine derivatives, their production and their pharmaceutical use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-02-16 | — | — | EP | disclosed |
| US-5891895-A | POTASSIUM CHANNEL MODULATORS; ANGINA PECTORIS; HYPERTENSIVEAGENTS; CARDIOVASCULAR, RESPIRATORY SYSTEM, BRAIN, GASTROINTESTINAL AND UROGENITAL DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0802187-A1 | Hydroxypyridine derivatives, their production and their pharmaceutical use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-22 | — | — | EP | disclosed |