SCHEMBL514887

SCHEMBL514887

COCOC(=O)c1cccc(Br)c1

nearest known ligand 0.60

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.60
MAPK1 P28482 1/20 0.60
LMNA P02545 1/20 0.58
TSHR P16473 1/20 0.58
PARP1 P09874 1/20 0.49
GAA P10253 1/20 0.48
HPGD P15428 1/20 0.48
NFKB1 P19838 1/20 0.48
NFKB2 Q00653 1/20 0.48
RELA Q04206 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
L3MBTL1 Q9Y468 3/20 0.47
RXFP1 Q9HBX9 1/20 0.47
CYP1A2 P05177 1/20 0.47
ATM Q13315 1/20 0.45
TDP1 Q9NUW8 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29627840 0.84 KDM4E (0.65) KDM4EMAPK1LMNATSHRSMN1; SMN2
SCHEMBL245137 0.84 KDM4E (0.65) KDM4EMAPK1LMNATSHRSMN1; SMN2
SCHEMBL9464044 0.84 MAPK1 (0.51) KDM4EMAPK1LMNATSHRPARP1
SCHEMBL514886 0.83 MAPK1 (0.56) KDM4EMAPK1LMNATSHRPARP1
SCHEMBL27468716 0.83 LOXL2 (0.56) KDM4ELMNATSHRHPGDSMN1; SMN2
SCHEMBL15344554 0.81 LMNA (0.68) KDM4EMAPK1LMNATSHRPARP1
SCHEMBL10226607 0.81 CYP4F2 (0.45) KDM4EMAPK1LMNASMN1; SMN2
SCHEMBL7914672 0.81 LOXL2 (0.50) KDM4ELMNATSHRSMN1; SMN2TDP1
SCHEMBL29818019 0.80 KDM4E (0.59) KDM4EMAPK1LMNATSHRPARP1
SCHEMBL145700 0.80 KDM4E (0.59) KDM4EMAPK1LMNATSHRPARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023210623-A1 HALOALKYL SULFONE ANILIDE COMPOUND AND HERBICIDE CONTAINING SAME 株式会社エス・ディー・エス バイオテック 2023-11-02 WO disclosed
WO-2014184071-A1 MIXTURES OF HALOALKYLSULFONANILIDE DERIVATIVES AND HERBICIDES SYNGENTA LIMITED (GB) 2014-11-20 WO disclosed
WO-2014184070-A1 MIXTURES OF HALOALKYLSULFONANILIDE DERIVATIVES AND HERBICIDES SYNGENTA LIMITED (GB) 2014-11-20 WO disclosed
EP-2420493-A1 HALOALKYLSULFONANILIDE DERIVATIVE Nissan Chemical Industries, Ltd. (JP) 2012-02-22 EP disclosed
US-20120029187-A1 HALOALKYLSULFONANILIDE DERIVATIVE NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-02-02 US disclosed
EP-2336104-A1 ORTHO-SUBSTITUTED HALOALKYLSULFONANILIDE DERIVATIVE AND HERBICIDE Nissan Chemical Industries, Ltd. (JP) 2011-06-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120029187-A1 HALOALKYLSULFONANILIDE DERIVATIVE CBR3, CBR1, HDHD5 KDM4E 3260/4885MAPK1 1508/4885LMNA 4076/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.