Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BHMT | Q93088 | 11/20 | 0.46 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 2/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8024758 | 0.86 | BHMT (0.43) | BHMTBHMT2NOS2NOS3NOS1 | |
| SCHEMBL24154514 | 0.82 | NOS2 (0.47) | BHMTBHMT2NOS2NOS3NOS1 | |
| SCHEMBL8024937 | 0.82 | ARG1 (0.40) | BHMTBHMT2NOS2NOS3NOS1 | |
| SCHEMBL474911 | 0.82 | BHMT (0.67) | BHMTBHMT2NOS2NOS3NOS1 | |
| SCHEMBL2119412 | 0.82 | BHMT (0.67) | BHMTBHMT2NOS2NOS3NOS1 | |
| SCHEMBL474910 | 0.82 | BHMT (0.67) | BHMTBHMT2NOS2NOS3NOS1 | |
| SCHEMBL19538739 | 0.80 | BHMT (0.46) | BHMTBHMT2NOS2NOS3NOS1 | |
| Hydrochloric Acid SCHEMBL28941785 | 0.80 | BHMT (0.65) | BHMTBHMT2NOS2NOS3NOS1 | |
| SCHEMBL1262429 | 0.78 | — | — | |
| SCHEMBL9579082 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675133-B1 | 13-Substituted milbemycin derivatives, their preparation and use | SANKYO CO (JP) | 2000-01-12 | — | — | EP | disclosed |
| US-5614470-A | AGRICULTURAL ANTHELMINTIC, ACARICIDE, INSECTICIDE | SANKYO COMPANY, LIMITED (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0675133-A1 | 13-Substituted milbemycin derivatives, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1995-10-04 | — | — | EP | disclosed |