Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5135541 | 0.93 | FAAH (0.58) | GRIK1LMNAHDAC3HDAC1HDAC2 | |
| SCHEMBL865266 | 0.93 | FAAH (0.58) | GRIK1LMNAHDAC3HDAC1HDAC2 | |
| SCHEMBL1004196 | 0.89 | ANPEP (0.50) | LMNAFAAHSMN1; SMN2TRPA1EPHX1 | |
| SCHEMBL3623271 | 0.85 | GRIK1 (0.56) | GRIK1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL27754701 | 0.81 | GRIK1 (0.61) | GRIK1LMNAHDAC3HDAC1HDAC2 | |
| SCHEMBL10419193 | 0.81 | GRIK1 (0.57) | GRIK1LMNAHDAC3HDAC1HDAC2 | |
| SCHEMBL30812427 | 0.81 | NOS1 (0.51) | GRIK1LMNAHDAC3HDAC1HDAC2 | |
| SCHEMBL29032086 | 0.81 | GRIK1 (0.61) | GRIK1LMNAHDAC3HDAC1HDAC2 | |
| SCHEMBL7056683 | 0.80 | NPC1 (0.53) | GRIK1LMNAHDAC3HDAC1HDAC2 | |
| SCHEMBL7598869 | 0.80 | TSHR (0.51) | GRIK1LMNAHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020141734-A1 | METHOD FOR PREPARING CHIRAL GAMMA-LACTAM COMPOUND AND METAL COMPLEX THEREFOR | 기초과학연구원 | 2020-07-09 | — | — | WO | disclosed |
| WO-2000053198-A1 | INHIBITOR OF LIPOXYGENASE PATHWAYS | PHARMALINK INTERNATIONAL LIMITED (CN) | 2000-09-14 | — | — | WO | disclosed |