Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28221183 | 0.89 | MDM2 (0.53) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL3623271 | 0.83 | GRIK1 (0.56) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL29278935 | 0.81 | CES1 (0.47) | NPC1RAB9ATDP1MDM2MAPK1 | |
| SCHEMBL8021775 | 0.80 | GRIK1 (0.53) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL11781795 | 0.80 | CES2 (0.49) | NPC1RAB9AMDM2MAPK1SLC6A3 | |
| SCHEMBL7166939 | 0.79 | RAB9A (0.50) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL28005839 | 0.79 | TRPA1 (0.54) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL3227004 | 0.79 | CES1 (0.44) | NPC1RAB9ATDP1MDM2HDAC2 | |
| SCHEMBL637814 | 0.79 | GPR84 (0.53) | SLC6A3MMP2MMP9CES2LMNA | |
| SCHEMBL3170929 | 0.78 | TRPA1 (0.57) | NPC1RAB9ACASP3SENP8SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107875143-B | Application of -2 (E)-alkene -1- pentanone of 1-4 '-hydroxy phenyl -5- phenyl in pharmacy | 贵阳中医学院 | 2019-09-17 | — | — | CN | disclosed |
| EP-0811629-B1 | OPTICALLY ACTIVE BIDENTATE PHOSPHINE LIGAND/PALLADIUM COMPLEX | NISSAN CHEMICAL IND LTD (JP) | 2003-05-02 | — | — | EP | disclosed |
| US-5880301-A | CATALYSTS FOR PREPARATION OF OPTICALLY ACTIVE BETA-HYDROXYKETONES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1999-03-09 | — | — | US | disclosed |
| EP-0811629-A1 | OPTICALLY ACTIVE BIDENTATE PHOSPHINE LIGAND/PALLADIUM COMPLEX | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1997-12-10 | — | — | EP | disclosed |