Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 14/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 6/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8019067 | 0.89 | HTR6 (0.61) | HTR6RXFP1MAPTTP53 | |
| SCHEMBL8028518 | 0.88 | HTR6 (0.55) | HTR6RXFP1MAPTTP53 | |
| SCHEMBL8028247 | 0.83 | HTR6 (0.48) | HTR6RXFP1POLBMAPT | |
| SCHEMBL8021774 | 0.82 | RXFP1 (0.64) | HTR6RXFP1MAPTTP53 | |
| SCHEMBL8019456 | 0.81 | KDM4E (0.64) | HTR6RXFP1POLBMAPTTP53 | |
| SCHEMBL8019479 | 0.78 | HPGD (0.60) | HTR6RXFP1POLBMAPTTP53 | |
| SCHEMBL8019082 | 0.77 | HTR6 (0.48) | HTR6RXFP1POLBMAPTTP53 | |
| SCHEMBL8030780 | 0.76 | HTR6 (0.65) | HTR6RXFP1POLBMAPTTP53 | |
| SCHEMBL8030932 | 0.74 | RXFP1 (0.79) | HTR6RXFP1POLBMAPTTP53 | |
| SCHEMBL8018355 | 0.72 | HTR6 (0.57) | HTR6RXFP1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009093934-A2 | SUBSTITUTED 3-SULPHONYL-[1,2,3]TRIAZOLO [1,5-A]PYRIMIDINES-ANTAGONISTS OF SEROTONIN 5-HT6 RECEPTORS, MEDICINAL SUBSTANCE, PHARMACEUTICAL COMPOSITION, MEDICINAL PREPARATION AND METHODS FOR THE PRODUCTION THEREOF | ALLA CHEM, LLC (US) | 2009-07-30 | — | — | WO | disclosed |