Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.55 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | EDNRB | P24530 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MC3R | P41968 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2089538 | 0.92 | BCAT2 (0.55) | BCAT2RIPK1SMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL5462636 | 0.92 | BCAT2 (0.55) | BCAT2RIPK1SMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL5470948 | 0.92 | BCAT2 (0.55) | BCAT2RIPK1SMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL2743315 | 0.86 | HDAC3 (0.50) | BCAT2RIPK1SMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL8742857 | 0.86 | HDAC3 (0.50) | BCAT2RIPK1SMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL4219820 | 0.86 | HRH1 (0.57) | SMN1; SMN2CYP1A2CYP2D6PKMNPSR1 | |
| SCHEMBL6340374 | 0.83 | SLC6A3 (0.46) | BCAT2SMN1; SMN2CYP1A2CYP2D6PKM | |
| SCHEMBL5610050 | 0.82 | RIPK1 (0.52) | BCAT2RIPK1SMN1; SMN2AOC3LMNA | |
| SCHEMBL1061595 | 0.81 | EPHX1 (0.58) | BCAT2SMN1; SMN2CYP1A2CYP2D6PKM | |
| SCHEMBL7056680 | 0.81 | TDP1 (0.62) | RIPK1SMN1; SMN2CYP1A2LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020141734-A1 | METHOD FOR PREPARING CHIRAL GAMMA-LACTAM COMPOUND AND METAL COMPLEX THEREFOR | 기초과학연구원 | 2020-07-09 | — | — | WO | disclosed |
| WO-2000053198-A1 | INHIBITOR OF LIPOXYGENASE PATHWAYS | PHARMALINK INTERNATIONAL LIMITED (CN) | 2000-09-14 | — | — | WO | disclosed |