Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 5/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8482382 | 0.81 | NOTUM (0.36) | MAPTKDM4EALDH1A1L3MBTL1NPC1 | |
| SCHEMBL10752085 | 0.77 | ALDH1A1 (0.32) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL1577055 | 0.73 | L3MBTL1 (0.32) | MAPTALDH1A1L3MBTL1NPC1RAB9A | |
| SCHEMBL10749142 | 0.72 | NOTUM (0.38) | MAPTKDM4EMEN1KMT2ANOTUM | |
| SCHEMBL10750163 | 0.72 | MAPT (0.37) | ARMAPTKDM4ENPC1RAB9A | |
| SCHEMBL10748422 | 0.69 | NOTUM (0.42) | ARCNR2KDM4ENPC1RAB9A | |
| SCHEMBL10752120 | 0.67 | SMN1; SMN2 (0.64) | MAPTKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL27471608 | 0.66 | AHR (0.56) | AHRCYP1B1ARCNR2MAPT | |
| SCHEMBL8920819 | 0.64 | AHR (0.43) | AHRCYP1B1MAPTKDM4EALDH1A1 | |
| SCHEMBL29769221 | 0.63 | AHR (1.00) | AHRCYP1B1MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0823462-B1 | Increasing the self-polishing properties of antifouling paints | SIGMA COATINGS BV (NL) | 2000-02-02 | — | — | EP | claimed |
| WO-1998005719-A1 | INCREASING THE SELF-POLISHING PROPERTIES OF ANTIFOULING PAINTS | SIGMA COATINGS B.V. (NL) | 1998-02-12 | — | — | WO | disclosed |