Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | DRD1 | P21728 | 3/20 | 0.45 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | HHAT | Q5VTY9 | 5/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | DRD5 | P21918 | 2/20 | 0.38 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22044650 | 1.00 | KMT2A (0.51) | KMT2ADRD1MAOADRD2DRD3 | |
| SCHEMBL20073821 | 0.79 | KMT2A (0.50) | KMT2ADRD1DRD2DRD3HHAT | |
| SCHEMBL20073820 | 0.79 | KMT2A (0.50) | KMT2ADRD1DRD2DRD3HHAT | |
| SCHEMBL21236284 | 0.78 | KMT2A (0.49) | KMT2ADRD1DRD2DRD3HHAT | |
| SCHEMBL8026946 | 0.77 | DRD2 (0.42) | KMT2ADRD1DRD2DRD3HHAT | |
| SCHEMBL22679819 | 0.77 | KMT2A (0.48) | KMT2ADRD1DRD2DRD3HHAT | |
| SCHEMBL8012736 | 0.77 | HHAT (0.38) | KMT2ADRD1DRD2DRD3HHAT | |
| SCHEMBL4751918 | 0.74 | DRD2 (0.42) | KMT2ADRD1DRD2DRD3HHAT | |
| SCHEMBL3303648 | 0.72 | MAOA (0.42) | DRD1MAOADRD2DRD3DRD4 | |
| SCHEMBL3303645 | 0.72 | MAOA (0.42) | DRD1MAOADRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3746444-B1 | CYCLOALKYL SUBSTITUTED PYRAZOLOPYRIMIDINES HAVING ACTIVITY AGAINST RSV | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2023-09-27 | — | — | EP | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| WO-2009095253-A1 | 6-HALO-PYRAZOLO[1, 5-A]PYRIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR (MGLUR) MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2009-08-06 | — | — | WO | disclosed |
| US-7235538-B2 | Heterocyclic compounds, which are inhibitors of the enzyme DPP-IV | NOVO NORDISK A/S (DK) | 2007-06-26 | — | — | US | disclosed |
| US-7235538-B2 | Heterocyclic compounds, which are inhibitors of the enzyme DPP-IV | NOVO NORDISK A/S (DK) | 2007-06-26 | — | — | US | disclosed |