Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HHAT | Q5VTY9 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8021988 | 0.77 | KMT2A (0.51) | HHATKMT2ADRD2DRD3DRD1 | |
| SCHEMBL22044650 | 0.77 | KMT2A (0.51) | HHATKMT2ADRD2DRD3DRD1 | |
| SCHEMBL8026946 | 0.72 | DRD2 (0.42) | HHATKMT2ADRD2DRD3DRD1 | |
| SCHEMBL8025796 | 0.70 | PRCP (0.56) | DRD2DRD1DRD4DRD5 | |
| SCHEMBL8030400 | 0.67 | MEN1 (0.42) | KMT2ADRD2DRD3DRD1DRD4 | |
| SCHEMBL8030423 | 0.67 | SRD5A1 (0.43) | DRD2DRD1DRD4 | |
| SCHEMBL8032022 | 0.67 | HTR2A (0.43) | DRD2 | |
| SCHEMBL4751918 | 0.67 | DRD2 (0.42) | HHATKMT2ADRD2DRD3DRD1 | |
| SCHEMBL22679819 | 0.66 | KMT2A (0.48) | HHATKMT2ADRD2DRD3DRD1 | |
| SCHEMBL2836823 | 0.66 | DRD1 (0.41) | HHATKMT2ADRD2DRD3DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009095253-A1 | 6-HALO-PYRAZOLO[1, 5-A]PYRIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR (MGLUR) MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2009-08-06 | — | — | WO | disclosed |