Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28448693 | 0.83 | TDP1 (0.32) | TDP1 | |
| SCHEMBL31042980 | 0.72 | MAPK1 (0.40) | TDP1L3MBTL1 | |
| SCHEMBL8986433 | 0.71 | TDP1 (0.66) | TDP1L3MBTL1 | |
| SCHEMBL3569028 | 0.70 | MEN1 (0.37) | TDP1KMT2A | |
| SCHEMBL8409269 | 0.69 | TDP1 (0.33) | TDP1 | |
| SCHEMBL11044076 | 0.68 | TDP1 (0.47) | TDP1L3MBTL1 | |
| SCHEMBL23967716 | 0.68 | PLG (0.34) | TDP1PKMKMT2A | |
| SCHEMBL22953453 | 0.68 | PLG (0.34) | TDP1PKMKMT2A | |
| SCHEMBL12852976 | 0.68 | PLG (0.34) | TDP1PKMKMT2A | |
| SCHEMBL28691609 | 0.67 | TDP1 (0.32) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784431-B1 | SYNERGISTIC ACTIVE SUBSTANCE HERBICIDE COMBINATIONS WITH 1-(2,6-DICHLORO-4-DIFLUOROMETHYL-PHENYL)-5-(2-CHLOROPROPIONAMIDO)-4-NITROPYRAZOL | BAYER AG (DE) | 2000-03-08 | — | — | EP | claimed |
| US-5344810-A | Synergistic triazine derivative mixture | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1994-09-06 | — | — | US | claimed |
| US-5990044-A | Selective herbicides based on aryl uracils | BAYER AKTIENGESELLSCHAFT (DE) | 1999-11-23 | — | — | US | disclosed |