SCHEMBL11044076

SCHEMBL11044076

Nc1c(Cl)c(F)nc(C(=O)C(=O)O)c1Cl

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.47
MAPT P10636 2/20 0.32
ATM Q13315 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
LMNA P02545 1/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8986433 0.85 TDP1 (0.66) TDP1MAPTATML3MBTL1LMNA
SCHEMBL29131534 0.78 TDP1 (0.43) TDP1MAPTATML3MBTL1LMNA
Potassium Ion SCHEMBL8986486 0.78 TDP1 (0.43) TDP1MAPTATML3MBTL1LMNA
SCHEMBL3569028 0.72 MEN1 (0.37) TDP1GAA
SCHEMBL3216266 0.69 TDP1 (0.38) TDP1
SCHEMBL8021999 0.68 TDP1 (0.37) TDP1L3MBTL1
SCHEMBL8409269 0.67 TDP1 (0.33) TDP1
SCHEMBL5941062 0.67 TDP1 (0.33) TDP1
Fluroxypyr SCHEMBL23545 0.66 TDP1 (0.35) TDP1
Fluroxypyr SCHEMBL29396793 0.66 TDP1 (0.35) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0101168-A2 Herbicidal mixtures SCHERING AGROCHEMICALS LIMITED (GB) 1984-02-22 EP claimed
EP-0101168-A2 Herbicidal mixtures SCHERING AGROCHEMICALS LIMITED (GB) 1984-02-22 EP disclosed
EP-0101168-A2 Herbicidal mixtures SCHERING AGROCHEMICALS LIMITED (GB) 1984-02-22 EP disclosed