Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 7/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8021996 | 1.00 | NPC1 (0.49) | NPC1ALDH1A1RAB9ACYP1A2SMN1; SMN2 | |
| SCHEMBL8026284 | 0.90 | NPC1 (0.54) | NPC1ALDH1A1RAB9ACYP1A2SMN1; SMN2 | |
| SCHEMBL8026280 | 0.87 | NPC1 (0.48) | NPC1ALDH1A1RAB9ACYP1A2SMN1; SMN2 | |
| SCHEMBL8026283 | 0.87 | NPC1 (0.48) | NPC1ALDH1A1RAB9ACYP1A2SMN1; SMN2 | |
| SCHEMBL9455956 | 0.79 | EPHX1 (0.47) | — | |
| SCHEMBL26802232 | 0.78 | NPC1 (0.56) | NPC1ALDH1A1RAB9ACYP1A2SMN1; SMN2 | |
| SCHEMBL9455979 | 0.76 | MTNR1A (0.43) | NPC1ALDH1A1CYP1A2KMT2AMEN1 | |
| SCHEMBL30239922 | 0.76 | LMNA (0.63) | NPC1ALDH1A1RAB9ACYP1A2SMN1; SMN2 | |
| SCHEMBL3141164 | 0.76 | LMNA (0.63) | NPC1ALDH1A1RAB9ACYP1A2SMN1; SMN2 | |
| SCHEMBL8024241 | 0.75 | NOTUM (0.41) | ALDH1A1RAB9AKMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975587-A1 | OXIME ETHER COMPOUNDS, THEIR USE AND INTERMEDIATES FOR PREPARATIONS OF THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998043949-A1 | OXIME ETHER COMPOUNDS, THEIR USE AND INTERMEDIATES FOR PREPARATIONS OF THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-10-08 | — | — | WO | disclosed |