Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8022000 | 0.90 | NPC1 (0.49) | NPC1RAB9AALDH1A1KMT2AMEN1 | |
| SCHEMBL8021996 | 0.90 | NPC1 (0.49) | NPC1RAB9AALDH1A1KMT2AMEN1 | |
| SCHEMBL8026280 | 0.88 | NPC1 (0.48) | NPC1RAB9AALDH1A1KMT2AMEN1 | |
| SCHEMBL8026283 | 0.88 | NPC1 (0.48) | NPC1RAB9AALDH1A1KMT2AMEN1 | |
| SCHEMBL8486182 | 0.83 | CES2 (0.41) | NPC1RAB9AALDH1A1KMT2AMEN1 | |
| SCHEMBL7695022 | 0.81 | LMNA (0.57) | NPC1RAB9AALDH1A1KMT2AMEN1 | |
| SCHEMBL26802232 | 0.79 | NPC1 (0.56) | NPC1RAB9AALDH1A1KMT2AMEN1 | |
| SCHEMBL29589944 | 0.78 | CES2 (0.74) | NPC1RAB9AALDH1A1KMT2AMEN1 | |
| SCHEMBL52445 | 0.78 | CES2 (0.74) | NPC1RAB9AALDH1A1KMT2AMEN1 | |
| SCHEMBL28126653 | 0.78 | CES2 (0.74) | NPC1RAB9AALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975587-A1 | OXIME ETHER COMPOUNDS, THEIR USE AND INTERMEDIATES FOR PREPARATIONS OF THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998043949-A1 | OXIME ETHER COMPOUNDS, THEIR USE AND INTERMEDIATES FOR PREPARATIONS OF THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-10-08 | — | — | WO | disclosed |