Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.55 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.55 |
| ▸ | PTPN5 | P54829 | 4/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10772495 | 0.98 | GABRA1 (0.53) | GABRA1GABRB2PTPN5PTPN2PTGDR2 | |
| SCHEMBL2916746 | 0.98 | GABRA1 (0.53) | GABRA1GABRB2PTPN5PTPN2PTGDR2 | |
| SCHEMBL2047127 | 0.93 | GABRA1 (0.59) | GABRA1GABRB2PTPN5PTPN2KMT2A | |
| SCHEMBL11598412 | 0.85 | PTPN5 (0.39) | GABRA1GABRB2PTPN5PTPN2PTGDR2 | |
| SCHEMBL4058553 | 0.84 | PTGDR2 (0.41) | PTPN5PTPN2PTGDR2NAAAKMT2A | |
| SCHEMBL10788064 | 0.82 | ALOX5 (0.44) | HTR1DHTR1B | |
| SCHEMBL27728789 | 0.82 | PTGDR2 (0.40) | PTPN5PTPN2PTGDR2NAAAKMT2A | |
| SCHEMBL1998542 | 0.81 | PTGDR2 (0.47) | PTPN5PTPN2PTGDR2NAAATHRB | |
| SCHEMBL27892012 | 0.81 | PTGDR2 (0.40) | GABRA1GABRB2PTPN5PTPN2PTGDR2 | |
| SCHEMBL12474580 | 0.81 | PTGDR2 (0.44) | PTGDR2NAAAKMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0984912-A1 | METHOD FOR CONTINUOUS PRODUCTION OF DIHYDROXYDIPHENYLALKANES | Bayer Aktiengesellschaft (DE) | 2000-03-15 | — | — | EP | disclosed |
| WO-1998052896-A1 | METHOD FOR CONTINUOUS PRODUCTION OF DIHYDROXYDIPHENYLALKANES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-26 | — | — | WO | disclosed |