SCHEMBL802219

SCHEMBL802219

CCC(C)(C)C(=O)NC(C)(C)CS(=O)(=O)O

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 4/20 0.35
EPHX1 P07099 1/20 0.33
POLB P06746 3/20 0.32
LMNA P02545 2/20 0.32
GRK2 P25098 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
APAF1 O14727 1/20 0.30
DNMT1 P26358 1/20 0.30
PTPN7 P35236 1/20 0.30
RECQL P46063 1/20 0.30
BLM P54132 1/20 0.30
PPP1CA P62136 1/20 0.30
CTDSP1 Q9GZU7 1/20 0.30
PTPN22 Q9Y2R2 1/20 0.30
CNR1 P21554 2/20 0.30
CNR2 P34972 2/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20043194 0.82 L3MBTL1 (0.33) POLBLMNAGRK2L3MBTL1MEN1
SCHEMBL13871736 0.81 ALDH1A1 (0.34) RIPK1EPHX1CNR2
SCHEMBL12716773 0.80 POLB (0.31) EPHX1POLBLMNAGRK2L3MBTL1
SCHEMBL6362808 0.80 MEN1 (0.35) RIPK1POLBLMNAGRK2L3MBTL1
SCHEMBL10027502 0.80
SCHEMBL15461822 0.79
SCHEMBL10063312 0.79 EPHX1 (0.42) RIPK1EPHX1POLBLMNAL3MBTL1
SCHEMBL23502428 0.79 ALDH1A1 (0.36) EPHX1POLBLMNAGRK2L3MBTL1
SCHEMBL13656121 0.79 RIPK1 (0.32) RIPK1
SCHEMBL13656128 0.79 RIPK1 (0.32) RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 175 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12044968-B2 Protective film-forming composition having acetal structure and amide structure NISSAN CHEMICAL CORPORATION (JP) 2024-07-23 US disclosed
US-12044968-B2 Protective film-forming composition having acetal structure and amide structure NISSAN CHEMICAL CORPORATION (JP) 2024-07-23 US disclosed
US-20230295457-A1 SURFACE TREATMENT LIQUID AND SURFACE TREATMENT METHOD TOKYO OHKA KOGYO CO., LTD. (JP) 2023-09-21 US disclosed
US-11745531-B2 Printing plate precursor, printing plate precursor laminate, method for making printing plate, and printing method FUJIFILM CORPORATION (JP) 2023-09-05 US disclosed
US-20230257614-A1 INK SET FOR PERMEABLE SUBSTRATE AND IMAGE RECORDING METHOD FUJIFILM CORPORATION (JP) 2023-08-17 US disclosed
US-20230229083-A1 PHOTORESIST COMPOSITIONS FOR EUV AND METHODS FOR MANUFACTURING SEMICONDUCTOR DEVICES USING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-07-20 US disclosed
US-20230229083-A1 PHOTORESIST COMPOSITIONS FOR EUV AND METHODS FOR MANUFACTURING SEMICONDUCTOR DEVICES USING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-07-20 US disclosed
US-11370862-B2 Radiation-sensitive composition, planographic printing plate precursor, and plate-making method for planographic printing plate FUJIFILM CORPORATION (JP) 2022-06-28 US disclosed
US-11034684-B2 Isoxazole analogs as FXR agonists and methods of use thereof ENANTA PHARMACEUTICALS, INC. (US) 2021-06-15 US disclosed
US-10689391-B2 Isoxazole analogs as FXR agonists and methods of use thereof ENANTA PHARMACEUTICALS, INC. (US) 2020-06-23 US disclosed
US-20080087183-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2008-04-17 US disclosed
US-20080070158-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD FOR PREPARATION OF LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2008-03-20 US disclosed
US-7314698-B2 Polymerizable composition and planographic printing plate precursor using the same FUJIFILM CORPORATION (JP) 2008-01-01 US disclosed
US-7279539-B2 Alkali-soluble polymer and polymerizable composition thereof FUJIFILM CORPORATION (JP) 2007-10-09 US disclosed
US-20070134587-A1 Lithographic printing plate precursor and lithographic printing method FUJI PHOTO FILM CO., LTD. 2007-06-14 US disclosed
US-20070072119-A1 Lithographic printing plate precursor and lithographic printing method FUJI PHOTO FILM CO., LTD. 2007-03-29 US disclosed
US-20070059627-A1 Polymer having a sulfonic group or a sulfonate group and an amide group and method of producing same CANON KABUSHIKI KAISHA (JP) 2007-03-15 US disclosed
US-7189500-B2 Photothermographic image-recording material FUJI PHOTO FILM CO., LTD. (JP) 2007-03-13 US disclosed
US-20070039500-A1 Manufacturing method of lithographic printing plate and manufacturing apparatus of lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2007-02-22 US disclosed
US-20070042293-A1 Including an aromatic diphosphonium compound along with an addition polymerization promoter, unsaturated compound, protective layeron an sluminium support; laser recording having excellent ink receptibility during printing and printing durability; strength; on-press development; image strength FUJI PHOTO FILM CO., LTD. 2007-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11034684-B2 Isoxazole analogs as FXR agonists and methods of use thereof GPBAR1, SLC10A1, NR1H4 RIPK1 3000/4885EPHX1 607/4885POLB 3719/4885
US-10689391-B2 Isoxazole analogs as FXR agonists and methods of use thereof SLC10A1, NR1H4, GPBAR1 RIPK1 3113/4885EPHX1 806/4885POLB 3989/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.