SCHEMBL8022276

SCHEMBL8022276

CCC[SiH]1CCC(C2CCC(CCc3ccc(-c4cc(F)c(F)c(F)c4)cc3)CC2)CC1

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.33
MAOB P27338 2/20 0.32
MAOA P21397 1/20 0.32
CTSC P53634 2/20 0.32
RARB P10826 2/20 0.32
RARA P10276 1/20 0.32
RARG P13631 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8022275 1.00 GPR84 (0.33) GPR84MAOBMAOACTSCRARB
SCHEMBL9012844 0.93 MAOB (0.34) GPR84MAOBMAOACTSCRARB
SCHEMBL9012840 0.93 MAOB (0.34) GPR84MAOBMAOACTSCRARB
SCHEMBL8006018 0.91 CYP17A1 (0.34) GPR84MAOBMAOARARBRARA
SCHEMBL8006014 0.91 CYP17A1 (0.34) GPR84MAOBMAOARARBRARA
SCHEMBL7756524 0.91 CYP17A1 (0.34) GPR84MAOBMAOARARBRARA
SCHEMBL8015049 0.88 MAOB (0.40) GPR84MAOBMAOA
SCHEMBL8015052 0.88 MAOB (0.40) GPR84MAOBMAOA
SCHEMBL8015048 0.88 MAOB (0.40) GPR84MAOBMAOA
SCHEMBL7753075 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0670322-B1 A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it SHINETSU CHEMICAL CO (JP) 2000-01-19 EP disclosed
US-5582764-A Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-12-10 US disclosed
EP-0670322-A1 A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it Shin-Etsu Chemical Co., Ltd. (JP) 1995-09-06 EP disclosed