SCHEMBL9012844

SCHEMBL9012844

CCC[SiH]1CCC(CCc2ccc(-c3cc(F)c(F)c(F)c3)cc2)CC1

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.34
MAOA P21397 1/20 0.34
RARB P10826 2/20 0.34
RARA P10276 1/20 0.34
RARG P13631 1/20 0.34
GPR84 Q9NQS5 1/20 0.33
HRH3 Q9Y5N1 1/20 0.31
CTSC P53634 1/20 0.30
F10 P00742 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9012840 1.00 MAOB (0.34) MAOBMAOARARBRARARARG
SCHEMBL8022276 0.93 GPR84 (0.33) MAOBMAOARARBRARARARG
SCHEMBL8022275 0.93 GPR84 (0.33) MAOBMAOARARBRARARARG
SCHEMBL8021369 0.90 CYP17A1 (0.37) MAOBMAOARARBRARARARG
SCHEMBL8021366 0.90 CYP17A1 (0.37) MAOBMAOARARBRARARARG
SCHEMBL8092154 0.87 MAOB (0.43) MAOBMAOAGPR84
SCHEMBL8092153 0.87 MAOB (0.43) MAOBMAOAGPR84
SCHEMBL9012850 0.87 RARB (0.31) MAOBMAOARARB
SCHEMBL9012848 0.87 RARB (0.31) MAOBMAOARARB
SCHEMBL8814984 0.84 GPR84 (0.40) MAOBMAOARARBRARARARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5523440-A Silacyclohexane compound, a method of preparaing it and a liquid crystal composition containing it SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-06-04 US disclosed
EP-0668286-A1 A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it Shin-Etsu Chemical Co., Ltd. (JP) 1995-08-23 EP disclosed