SCHEMBL802228

SCHEMBL802228

Oc1cccc2cc3ccccc3nc12

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.61
ALDH1A1 P00352 6/20 0.61
KMT2A Q03164 3/20 0.61
MAPT P10636 2/20 0.61
GAA P10253 2/20 0.61
RAB9A P51151 1/20 0.61
NPSR1 Q6W5P4 1/20 0.61
HPGD P15428 3/20 0.56
GLA P06280 2/20 0.56
KDM4E B2RXH2 6/20 0.52
STAT3 P40763 1/20 0.52
NQO2 P16083 2/20 0.52
CYP1A2 P05177 2/20 0.50
MEN1 O00255 2/20 0.47
METAP2 P50579 2/20 0.47
PLAU P00749 1/20 0.47
NCF1 P14598 1/20 0.47
CYP3A4 P08684 1/20 0.46
CYP2C9 P11712 1/20 0.46
ALOX12 P18054 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31746104 0.98 ACHE (0.59) ACHEALDH1A1KMT2AMAPTGAA
SCHEMBL2392615 0.98 ACHE (0.59) ACHEALDH1A1KMT2AMAPTGAA
SCHEMBL3246323 0.84 METAP2 (0.56) ACHEALDH1A1KMT2AMAPTGAA
SCHEMBL14610638 0.80 METAP2 (0.57) ACHEALDH1A1KMT2AMAPTGAA
SCHEMBL4902020 0.80 ALDH1A1 (0.70) ACHEALDH1A1KMT2AMAPTGAA
SCHEMBL18387564 0.78 ALDH1A1 (0.77) ACHEALDH1A1KMT2AMAPTGAA
SCHEMBL11059581 0.77 NQO2 (0.50) ACHEALDH1A1KMT2AMAPTGAA
SCHEMBL11376771 0.77 ALDH1A1 (0.55) ACHEALDH1A1KMT2AMAPTGAA
SCHEMBL3181469 0.77 ACHE (1.00) ACHEALDH1A1KMT2AMAPTGAA
SCHEMBL345562 0.76 ALDH1A1 (1.00) ACHEALDH1A1KMT2AMAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 258 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2265677-B1 CORROSION DETECTION PRODUCT AND METHOD BATTELLE MEMORIAL INSTITUTE (US) 2019-05-15 EP claimed
EP-2493956-B1 MOISTURE-CURING FORMULATIONS WITH TIME-MODIFIED CURING BEHAVIOR HENKEL AG & CO KGAA (DE) 2018-04-18 EP claimed
CN-102712751-B Moisture-curing formulations with time-modified phases HENKEL AG & CO KGAA 2015-06-10 CN claimed
US-8592517-B2 Moisture-curing formulations with time-modified phases HENKEL AG & CO. KGAA (DE) 2013-11-26 US claimed
US-20120277373-A1 MOISTURE-CURING FORMULATIONS WITH TIME-MODIFIED PHASES HENKEL AG & CO. KGAA (DE) 2012-11-01 US claimed
EP-1558585-A4 NEUROLOGICALLY-ACTIVE COMPOUNDS PRANA BIOTECHNOLOGY LTD (AU) 2008-07-02 EP claimed
CN-1720238-A Neurologically-active compounds PRANA BIOTECHNOLOGY LTD (AU) 2006-01-11 CN claimed
WO-2005108372-A1 PROCESS TO MAKE METAL COMPLEXES WITH VOLATILE LIQUID METAL COMPOUNDS ALBEMARLE CORPORATION (US) 2005-11-17 WO claimed
EP-1558585-A1 NEUROLOGICALLY-ACTIVE COMPOUNDS Prana Biotechnology Ltd (AU) 2005-08-03 EP claimed
WO-2004031161-A1 NEUROLOGICALLY-ACTIVE COMPOUNDS PRANA BIOTECHNOLOGY LIMITED (AU) 2004-04-15 WO claimed
EP-0737722-B1 New indoaniline metal complex, process for their production, and transparent recording medium and optical recording medium by use thereof JUJO PAPER CO LTD (JP) 2001-07-04 EP claimed
EP-0737722-A2 New indoaniline metal complex, process for their production, and transparent recording medium and optical recording medium by use thereof NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1996-10-16 EP claimed
EP-0377357-B1 Process for the condensation of at least one epoxide on at least one cyclic anhyhride in the presence of a titanium-based catalyst INST FRANCAIS DU PETROLE (FR) 1994-03-23 EP claimed
EP-0387119-B1 Process for the condensation of at least one epoxide with at least one cyclic anhydride in the presence of a catalyst based on at least one nitrogen containing titanium complex INST FRANCAIS DU PETROLE (FR) 1993-11-18 EP claimed
US-5001227-A Fibre-reactive 1:1 chromium complex azo or azomethine dyes having a bidentate chelating group and a monofunctional neutral ligand CIBA-GEIGY CORPORATION (US) 1991-03-19 US claimed
US-3982999-A LEUKEMIA KHARASCH JEROME A 1976-09-28 US claimed
JP-7166159-A None JP disclosed
JP-4198191-A None JP disclosed
US-4009150-A CHELATE COMPOUNDS, REDUCING AGENTS, INITIATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-02-22 US disclosed
US-3982999-A LEUKEMIA KHARASCH JEROME A 1976-09-28 US disclosed