Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | RAF1 | P04049 | 2/20 | 0.49 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | CTSV | O60911 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8034161 | 0.92 | APP (0.47) | MEN1KMT2ARAF1MAP2K1HPGD | |
| SCHEMBL8035939 | 0.89 | RAF1 (0.44) | MEN1KMT2ARAF1MAP2K1HPGD | |
| SCHEMBL8031650 | 0.87 | MEN1 (0.46) | MEN1KMT2ARAF1MAP2K1HPGD | |
| SCHEMBL8022338 | 0.85 | TRPM8 (0.46) | MEN1KMT2ARAF1MAP2K1HPGD | |
| SCHEMBL8039011 | 0.85 | HSP90AA1 (0.53) | MEN1KMT2AHPGDGAARXFP1 | |
| SCHEMBL8034163 | 0.85 | CTSV (0.47) | MEN1KMT2ARAF1MAP2K1HPGD | |
| SCHEMBL8035938 | 0.83 | SRD5A1 (0.47) | MEN1KMT2ARAF1MAP2K1HPGD | |
| SCHEMBL8038345 | 0.82 | HPGD (0.52) | MEN1KMT2ARAF1MAP2K1HPGD | |
| SCHEMBL8032086 | 0.81 | NPC1 (0.47) | MEN1KMT2ARAF1MAP2K1HPGD | |
| SCHEMBL8041162 | 0.81 | CTSV (0.60) | HPGDSRD5A1SRD5A2CTSVCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081892-A1 | NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THOSE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-02 | — | — | WO | disclosed |