Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 2/20 | 0.44 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | CTSV | O60911 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8034161 | 0.89 | APP (0.47) | RAF1MAP2K1EGFRMEN1KMT2A | |
| SCHEMBL8022341 | 0.89 | MEN1 (0.50) | RAF1MAP2K1EGFRMEN1KMT2A | |
| SCHEMBL8031650 | 0.83 | MEN1 (0.46) | RAF1MAP2K1EGFRMEN1KMT2A | |
| SCHEMBL8022338 | 0.81 | TRPM8 (0.46) | RAF1MAP2K1EGFRMEN1KMT2A | |
| SCHEMBL8034163 | 0.81 | CTSV (0.47) | RAF1MAP2K1EGFRMEN1KMT2A | |
| SCHEMBL8039019 | 0.80 | HSP90AA1 (0.39) | MEN1KMT2AHDAC1HDAC6APP | |
| SCHEMBL8035938 | 0.79 | SRD5A1 (0.47) | RAF1MAP2K1EGFRMEN1KMT2A | |
| SCHEMBL8038345 | 0.78 | HPGD (0.52) | RAF1MAP2K1EGFRMEN1KMT2A | |
| SCHEMBL8032086 | 0.77 | NPC1 (0.47) | RAF1MAP2K1EGFRMEN1KMT2A | |
| SCHEMBL8041162 | 0.77 | CTSV (0.60) | SRD5A1SRD5A2SMPD1HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081892-A1 | NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THOSE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-02 | — | — | WO | disclosed |