Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7659006 | 0.80 | RAD51 (0.48) | MEN1KMT2ATP53CYP1A2CYP3A4 | |
| SCHEMBL7659067 | 0.80 | RAD51 (0.48) | MEN1KMT2ATP53CYP1A2CYP3A4 | |
| SCHEMBL8019545 | 0.80 | TP53 (0.48) | MEN1KMT2ATP53CYP1A2CYP3A4 | |
| SCHEMBL7657142 | 0.78 | ALDH1A1 (0.63) | MEN1KMT2ATP53CYP1A2CYP3A4 | |
| SCHEMBL8024683 | 0.74 | RAB9A (0.66) | MEN1KMT2AGAAMAPTLMNA | |
| SCHEMBL8027954 | 0.72 | LMNA (0.57) | MEN1KMT2ATP53GAAMAPT | |
| SCHEMBL11240994 | 0.70 | SMN1; SMN2 (0.58) | MEN1KMT2ATP53CYP1A2CYP3A4 | |
| SCHEMBL8019216 | 0.70 | MAPT (0.63) | MEN1KMT2ATP53MAPTLMNA | |
| SCHEMBL7662975 | 0.69 | CYP1A2 (0.57) | MEN1KMT2ATP53CYP1A2CYP3A4 | |
| SCHEMBL7663040 | 0.69 | CYP1A2 (0.57) | MEN1KMT2ATP53CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000058277-A1 | ARYL SULFONIC ACIDS AND DERIVATIVES AS FSH ANTAGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-10-05 | — | — | WO | disclosed |