Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.49 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | CDK9 | P50750 | 1/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7758738 | 0.87 | NAPRT (0.53) | NAPRTHSD17B10KMT2AMEN1NPC1 | |
| SCHEMBL7758743 | 0.87 | NAPRT (0.53) | NAPRTHSD17B10KMT2AMEN1NPC1 | |
| SCHEMBL6665605 | 0.78 | ALDH1A1 (0.46) | NAPRTHSD17B10KMT2AMEN1NPC1 | |
| SCHEMBL6657756 | 0.78 | ALDH1A1 (0.46) | NAPRTHSD17B10KMT2AMEN1NPC1 | |
| SCHEMBL6657749 | 0.78 | ALDH1A1 (0.46) | NAPRTHSD17B10KMT2AMEN1NPC1 | |
| SCHEMBL8511248 | 0.78 | NAPRT (0.61) | NAPRTHSD17B10KMT2AMEN1NPC1 | |
| SCHEMBL8511246 | 0.78 | NAPRT (0.61) | NAPRTHSD17B10KMT2AMEN1NPC1 | |
| SCHEMBL3858962 | 0.77 | ALDH1A1 (0.50) | NAPRTHSD17B10KMT2AMEN1NPC1 | |
| SCHEMBL2638458 | 0.76 | NAPRT (0.59) | NAPRTHSD17B10KMT2ANPC1RAB9A | |
| SCHEMBL10420669 | 0.76 | NAPRT (0.59) | NAPRTHSD17B10KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278595-B2 | Fungicides | ZENECA LTD (GB) | 2000-01-12 | — | — | EP | disclosed |
| EP-0472224-B1 | Fungicides | ZENECA LTD (GB) | 1994-04-27 | — | — | EP | disclosed |
| EP-0472224-A1 | Fungicides | ZENECA LIMITED (GB) | 1992-02-26 | — | — | EP | disclosed |