Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TNKS | O95271 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1710145 | 0.90 | MEN1 (0.38) | MEN1KMT2AALDH1A1HPGDGAA | |
| SCHEMBL8276444 | 0.77 | NOTUM (0.50) | MEN1KMT2AALDH1A1HPGDGAA | |
| SCHEMBL30100865 | 0.75 | TNKS (0.46) | MEN1KMT2AALDH1A1HPGDGAA | |
| SCHEMBL28466766 | 0.75 | TNKS (0.46) | MEN1KMT2AALDH1A1HPGDGAA | |
| SCHEMBL23601176 | 0.74 | NOTUM (0.50) | MEN1KMT2AALDH1A1HPGDGAA | |
| SCHEMBL13911374 | 0.74 | BCL2L1 (0.46) | TNKSPARP1TNKS2DRD2 | |
| SCHEMBL26630604 | 0.74 | TNKS (0.43) | MEN1KMT2AALDH1A1HPGDGAA | |
| SCHEMBL2625794 | 0.74 | NOTUM (0.50) | MEN1KMT2AALDH1A1HPGDGAA | |
| SCHEMBL6402604 | 0.74 | TNKS (0.43) | MEN1KMT2AALDH1A1HPGDGAA | |
| SCHEMBL19957595 | 0.74 | TNKS (0.43) | MEN1KMT2AALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009079624-A1 | 4-IMIDAZOLIDINONES AS KV1.5 POTASSIUM CHANNEL INHIBITORS | WYETH (US) | 2009-06-25 | — | — | WO | disclosed |