SCHEMBL8022860

SCHEMBL8022860

C=CCOc1ccc(-c2ccccc2C(=O)Oc2ccc(O)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 4/20 0.46
GAA P10253 4/20 0.46
SI P14410 4/20 0.46
MGAM2 Q2M2H8 4/20 0.46
ALDH2 P05091 1/20 0.46
MAOA P21397 1/20 0.46
MAOB P27338 1/20 0.46
BACE1 P56817 1/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
LMNA P02545 1/20 0.42
MAPT P10636 1/20 0.42
CYP3A4 P08684 1/20 0.42
POLB P06746 1/20 0.41
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40
SLC5A1 P13866 1/20 0.39
SLC5A2 P31639 1/20 0.39
CHRNB2 P17787 1/20 0.39
CHRNB4 P30926 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8922614 0.84 LIG1 (0.56) GAAMEN1KMT2ALMNAMAPT
SCHEMBL9735304 0.81 TSHR (0.50) GAAMEN1KMT2ALMNAMAPT
SCHEMBL8022856 0.81 RXRA (0.42) MGAMGAASIMGAM2ALDH2
SCHEMBL5846209 0.81 ADRB2 (0.39) BACE1MEN1KMT2AMAPTPOLB
SCHEMBL9446934 0.78 ADRB2 (0.48) KMT2AMAPTPOLBSLC5A1SLC5A2
SCHEMBL7626930 0.78 ADRB2 (0.48) KMT2AMAPTPOLBSLC5A1SLC5A2
SCHEMBL7157210 0.78 HSD17B10 (0.47) MEN1KMT2ALMNAMAPTPOLB
Phenol SCHEMBL7769420 0.76 MGAM (0.50) MGAMGAASIMGAM2ALDH2
SCHEMBL3421079 0.76 GAA (0.55) MGAMGAASIMGAM2ALDH2
SCHEMBL8825667 0.75 BACE1 (0.52) BACE1MEN1KMT2ALMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6040411-A Low glass temperature organosiloxanes CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 2000-03-21 US disclosed