Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.36 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13868023 | 0.87 | ALDH1A1 (0.40) | ALDH1A1KDM4ESMN1; SMN2NPC1TDP1 | |
| SCHEMBL8115818 | 0.85 | ALDH1A1 (0.41) | ALDH1A1KDM4ESMN1; SMN2NPC1GAA | |
| SCHEMBL13990506 | 0.85 | HSD11B1 (0.43) | ALDH1A1KDM4ESMN1; SMN2NPC1TDP1 | |
| SCHEMBL12263923 | 0.83 | TDP1 (0.39) | ALDH1A1SMN1; SMN2NPC1TDP1NPSR1 | |
| SCHEMBL21166378 | 0.82 | LMNA (0.37) | ALDH1A1KDM4ESMN1; SMN2NPC1TDP1 | |
| SCHEMBL13990721 | 0.79 | CYP1A2 (0.45) | ALDH1A1KDM4ESMN1; SMN2NPC1TDP1 | |
| SCHEMBL12898216 | 0.78 | KMT2A (0.39) | ALDH1A1KDM4ENPC1TDP1NPSR1 | |
| SCHEMBL12048608 | 0.76 | KDM4E (0.45) | ALDH1A1KDM4ESMN1; SMN2NPC1NPSR1 | |
| SCHEMBL16334247 | 0.76 | ALDH1A1 (0.45) | ALDH1A1KDM4ESMN1; SMN2NPC1TDP1 | |
| SCHEMBL10834448 | 0.76 | ALDH1A1 (0.45) | ALDH1A1KDM4ESMN1; SMN2NPC1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120071517-A1 | 2-PYRIDINYLETHYLCARBOXAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | BAYER SAS (FR) | 2012-03-22 | — | — | US | disclosed |
| US-20080312435-A1 | Imine Compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312435-A1 | Imine Compound | CNR1, CNR2, HRH4 | ALDH1A1 2674/4885KDM4E 3386/4885SMN1; SMN2 1844/4885 |
| US-20120071517-A1 | 2-PYRIDINYLETHYLCARBOXAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | CYP1A2, CYP51A1, CYP3A5 | ALDH1A1 831/4885KDM4E 501/4885SMN1; SMN2 3882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.