Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | TYMP | P19971 | 5/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6329773 | 0.92 | LMNA (0.62) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL6329768 | 0.92 | LMNA (0.62) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL2338508 | 0.92 | LMNA (0.62) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL8021661 | 0.89 | LMNA (0.52) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL8021664 | 0.89 | LMNA (0.52) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL2503960 | 0.82 | LMNA (0.58) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL2503954 | 0.82 | LMNA (0.58) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL17435236 | 0.80 | HK1 (0.47) | TYMP | |
| SCHEMBL20608732 | 0.80 | HK1 (0.47) | TYMP | |
| SCHEMBL14278404 | 0.80 | TSHR (0.52) | LMNAKMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711766-B1 | 7-FLUORO-2, 3-DIDEHYDROSIALIC ACID AND INTERMEDIATE FOR SYNTHESIS THEREOF | DAIKIN IND LTD (JP) | 2000-02-16 | — | — | EP | disclosed |
| US-5627290-A | 2,3-didehydrosialic acid substituted with fluorine at 7-position and synthetic intermediate thereof | DAIKIN INDUSTRIES, LTD. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0711766-A1 | 7-FLUORO-2, 3-DIDEHYDROSIALIC ACID AND INTERMEDIATE FOR SYNTHESIS THEREOF | DAIKIN INDUSTRIES, LIMITED (JP) | 1996-05-15 | — | — | EP | disclosed |