Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 3/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2338508 | 1.00 | LMNA (0.62) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL6329773 | 1.00 | LMNA (0.62) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL8023003 | 0.92 | LMNA (0.52) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL8021664 | 0.91 | LMNA (0.52) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL8021661 | 0.91 | LMNA (0.52) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL2334092 | 0.87 | LMNA (0.55) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL17435235 | 0.87 | LMNA (0.55) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL31540818 | 0.86 | LMNA (0.56) | LMNAKMT2APOLBALDH1A1TGM2 | |
| SCHEMBL2454844 | 0.86 | TSHR (0.52) | LMNAKMT2AALDH1A1TSHRCA1 | |
| SCHEMBL14278404 | 0.86 | TSHR (0.52) | LMNAKMT2AALDH1A1TSHRCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6858724-B2 | Non-mucin type synthetic compounds or its carrier conjugated compounds | KOTOBUKI PHARMACEUTICAL CO., LTD. (JP) | 2005-02-22 | — | — | US | disclosed |
| US-20020107224-A1 | Non-mucin type synthetic compounds or its carrier conjugated compounds | KOTOBUKI PHARMACEUTICAL CO., LTD. (JP) | 2002-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020107224-A1 | Non-mucin type synthetic compounds or its carrier conjugated compounds | MUC1, FUT5, ST6GAL1 | LMNA 4472/4885KMT2A 2303/4885POLB 1709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.