SCHEMBL20608732

SCHEMBL20608732

CC(=O)N[C@H]1C(O)[C@H](O)C(COC(c2ccccc2)(c2ccccc2)c2ccccc2)O[C@H]1O

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ HK1 P19367 3/20 0.47
▸ HK2 P52789 3/20 0.47
▸ TYMP P19971 9/20 0.45
▸ MAPK1 P28482 1/20 0.42
▸ HRAS P01112 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17435236 1.00 HK1 (0.47) HK1HK2TYMPMAPK1HRAS
SCHEMBL12812836 0.83 HK1 (0.43) HK1HK2TYMP
SCHEMBL12812835 0.83 HK1 (0.43) HK1HK2TYMP
SCHEMBL7235905 0.82 TYMP (0.45) TYMPMAPK1
SCHEMBL7235898 0.82 TYMP (0.45) TYMPMAPK1
SCHEMBL7774713 0.82 TP53 (0.47) TYMPMAPK1HRAS
SCHEMBL23113802 0.80 TYMP (0.49) HK1HK2TYMP
SCHEMBL3194070 0.80 TYMP (0.49) HK1HK2TYMP
SCHEMBL3194078 0.80 TYMP (0.49) HK1HK2TYMP
SCHEMBL8023003 0.80 LMNA (0.52) TYMP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12540219-B2 Method for deacetylation of biopolymers Galderma Holding SA (CH) 2026-02-03 — — US disclosed
US-12365768-B2 Method for deacetylation of biopolymers Galderma Holding SA (CH) 2025-07-22 — — US disclosed
EP-3397650-B1 HYDROLYSIS OF ESTER BONDS IN AMIDE CROSSLINKED GLYCOSAMINOGLYCANS GALDERMA SA (CH) 2025-05-14 — — EP disclosed
US-20240199822-A1 METHOD FOR PREPARING ACYLATED CROSSLINKED GLYCOSAMINOGLYCANS Galderma Holding SA (CH) 2024-06-20 — — US disclosed
US-11939433-B2 Method for preparing acylated crosslinked glycosaminoglycans GALDERMA HOLDING S.A. (CH) 2024-03-26 — — US disclosed
US-20230323041-A1 METHOD FOR PREPARING ACYLATED CROSSLINKED GLYCOSAMINOGLYCANS Galderma Holding SA (CH) 2023-10-12 — — US disclosed
US-11708461-B2 Method for preparing acylated crosslinked glycosaminoglycans Galderma Holding SA (CH) 2023-07-25 — — US disclosed
CN-116284867-A Method for deacetylation of biopolymers 高德美控股有限公司 2023-06-23 — — CN disclosed
CN-108779184-B Method for deacetylation of biopolymers 高德美控股有限公司 2023-04-21 — — CN disclosed
US-20220177655-A1 METHOD FOR DEACETYLATION OF BIOPOLYMERS Galderma Holding SA (CH) 2022-06-09 — — US disclosed
US-11066526-B2 Method for cleaving amide bonds Galderma Holding SA (CH) 2021-07-20 — — US disclosed
US-20210108036-A1 METHOD FOR PREPARING ACYLATED CROSSLINKED GLYCOSAMINOGLYCANS GALDERMA S.A. (CH) 2021-04-15 — — US disclosed
US-10954316-B2 Method for cleaving amide bonds Galderma Holding SA (CH) 2021-03-23 — — US disclosed
US-10899894-B2 Method for preparing acylated crosslinked glycosaminoglycans GALDERMA S.A (CH) 2021-01-26 — — US disclosed
EP-3397648-B1 METHOD FOR DEACETYLATION OF BIOPOLYMERS GALDERMA SA (CH) 2020-05-27 — — EP disclosed
EP-3397649-B1 METHOD FOR PREPARING ACYLATED CROSSLINKED GLYCOSAMINOGLYCANS GALDERMA SA (CH) 2020-05-27 — — EP disclosed
US-20200030219-A1 METHOD FOR PREPARING ACYLATED CROSSLINKED GLYCOSAMINOGLYCANS GALDERMA S.A. (CH) 2020-01-30 — — US disclosed
US-20190023855-A1 HYDROLYSIS OF ESTER BONDS IN AMIDE CROSSLINKED GLYCOSAMINOGLYCANS GALDERMA S.A. (CH) 2019-01-24 — — US disclosed
US-20190016830-A1 METHOD FOR DEACETYLATION OF BIOPOLYMERS GALDERMA S.A. (CH) 2019-01-17 — — US disclosed
US-20190010113-A1 METHOD FOR CLEAVING AMIDE BONDS GALDERMA S.A. (CH) 2019-01-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11939433-B2 Method for preparing acylated crosslinked glycosaminoglycans ALG1, CSGALNACT1, AMDHD2 HK1 2335/4885HK2 1634/4885TYMP 3311/4885
US-20240199822-A1 METHOD FOR PREPARING ACYLATED CROSSLINKED GLYCOSAMINOGLYCANS ALG1, CSGALNACT1, AMDHD2 HK1 2335/4885HK2 1634/4885TYMP 3311/4885
US-12540219-B2 Method for deacetylation of biopolymers CA12, CA13, CA1 HK1 578/4885HK2 254/4885TYMP 2895/4885
US-11708461-B2 Method for preparing acylated crosslinked glycosaminoglycans ALG1, CSGALNACT1, AMDHD2 HK1 2335/4885HK2 1634/4885TYMP 3311/4885
US-20230323041-A1 METHOD FOR PREPARING ACYLATED CROSSLINKED GLYCOSAMINOGLYCANS ALG1, CSGALNACT1, AMDHD2 HK1 2335/4885HK2 1634/4885TYMP 3311/4885
US-20200030219-A1 METHOD FOR PREPARING ACYLATED CROSSLINKED GLYCOSAMINOGLYCANS ALG1, CSGALNACT1, AMDHD2 HK1 2335/4885HK2 1634/4885TYMP 3311/4885
US-20190023855-A1 HYDROLYSIS OF ESTER BONDS IN AMIDE CROSSLINKED GLYCOSAMINOGLYCANS AMDHD2, HPSE, ENGASE HK1 1630/4885HK2 1215/4885TYMP 2108/4885
US-20210108036-A1 METHOD FOR PREPARING ACYLATED CROSSLINKED GLYCOSAMINOGLYCANS ALG1, CSGALNACT1, AMDHD2 HK1 2335/4885HK2 1634/4885TYMP 3311/4885
US-20190010113-A1 METHOD FOR CLEAVING AMIDE BONDS DNPEP, NAAA, ASPH HK1 3626/4885HK2 3184/4885TYMP 2440/4885
US-11066526-B2 Method for cleaving amide bonds DNPEP, NAAA, ASPH HK1 3626/4885HK2 3184/4885TYMP 2440/4885
US-20220177655-A1 METHOD FOR DEACETYLATION OF BIOPOLYMERS AADAC, ALG1, AMDHD2 HK1 1555/4885HK2 1119/4885TYMP 2899/4885
US-12365768-B2 Method for deacetylation of biopolymers AADAC, ALG1, AMDHD2 HK1 1555/4885HK2 1119/4885TYMP 2899/4885
US-10899894-B2 Method for preparing acylated crosslinked glycosaminoglycans ALG1, CSGALNACT1, AMDHD2 HK1 2335/4885HK2 1634/4885TYMP 3311/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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