SCHEMBL8023325

SCHEMBL8023325

Cc1ccc(C(OB(O)O)(c2ccccc2)c2ccccc2)c(-c2ccccc2)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 1/20 0.40
HDAC7 Q8WUI4 1/20 0.38
CNR1 P21554 2/20 0.36
CNR2 P34972 2/20 0.36
PSMB5 P28074 1/20 0.34
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
LMNA P02545 2/20 0.33
MAPT P10636 2/20 0.33
GPR55 Q9Y2T6 1/20 0.33
KIF11 P52732 1/20 0.32
PTPN5 P54829 2/20 0.32
MAOB P27338 1/20 0.32
ESR2 Q92731 1/20 0.32
NUDT1 P36639 1/20 0.31
PIM1 P11309 1/20 0.31
KDM4E B2RXH2 2/20 0.31
ALDH1A1 P00352 2/20 0.31
BACE1 P56817 1/20 0.31
NPC1 O15118 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4642896 0.83 PTGDR2 (0.40) PTGDR2CNR1CNR2MEN1KMT2A
SCHEMBL8016450 0.83 KCNN4 (0.38) MAPTBACE1TP53PDK2
SCHEMBL5145264 0.82 ALDH1A1 (0.35) KIF11ALDH1A1BACE1CYP2C9
Ammonia Solution, Strong SCHEMBL9771960 0.80 ALDH1A1 (0.34) KIF11ALDH1A1BACE1CYP2C9
Ammonia Solution, Strong SCHEMBL9771953 0.80 ALDH1A1 (0.34) KIF11ALDH1A1BACE1CYP2C9
SCHEMBL8018642 0.78 CD274 (0.41) CNR1CNR2PTPN5ALDH1A1
SCHEMBL3371241 0.75 HDAC7 (0.44) PTGDR2HDAC7CNR1CNR2PSMB5
Benzene SCHEMBL27568485 0.72 KIF11 (0.40) KIF11ESR2ALDH1A1CYP1A2CYP3A4
SCHEMBL723986 0.72 KIF11 (0.40) KIF11ESR2ALDH1A1CYP1A2CYP3A4
SCHEMBL911318 0.72 MGLL (0.35) PTGDR2KIF11PTPN5MAOBBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6096794-A PHOTOINITIATOR SYSTEM FOR PHOTOPOLYMERIZATION OF ETHYLENICALLY UNSATURATED POLYMERIZABLE COMPOUNDS CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-08-01 US disclosed
US-6090865-A PHOTOINITIATOR SYSTEM COMPRISING (A) AT LEAST ONE O-ALKYLATED AROMATIC NITROGEN-HETEROCYCLE AMINE OXIDE CATION SALT AND (B) AT LEAST ONE ELECTRON DONOR COMPOUND. CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-07-18 US disclosed