SCHEMBL8023494

SCHEMBL8023494

COc1ccc(CC#CC=Cc2ccccc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.54
RAB9A P51151 2/20 0.49
LTA4H P09960 1/20 0.46
ALDH1A1 P00352 4/20 0.43
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
CYP1B1 Q16678 2/20 0.43
MAPT P10636 2/20 0.43
PPARG P37231 1/20 0.43
NFE2L2 Q16236 1/20 0.43
HSPD1 P10809 1/20 0.43
TNFRSF1A P19438 1/20 0.43
MAOB P27338 1/20 0.43
HSPE1 P61604 1/20 0.43
RELA Q04206 4/20 0.42
LMNA P02545 3/20 0.42
NFKB1 P19838 2/20 0.42
NFKB2 Q00653 2/20 0.42
KDM4E B2RXH2 2/20 0.42
HPGD P15428 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8023490 0.80 TRPA1 (0.59) TRPA1ALDH1A1MEN1KMT2ACYP1B1
SCHEMBL8023488 0.80 TRPA1 (0.59) TRPA1ALDH1A1MEN1KMT2ACYP1B1
SCHEMBL8530770 0.74 TUBB1 (0.49) TRPA1RAB9AALDH1A1MEN1KMT2A
SCHEMBL8530773 0.74 TUBB1 (0.49) TRPA1RAB9AALDH1A1MEN1KMT2A
SCHEMBL28304802 0.74 IDO1 (0.56) LTA4HALDH1A1MAPTMAOBKDM4E
SCHEMBL21244052 0.74 LTA4H (0.55) RAB9ALTA4HALDH1A1MEN1KMT2A
SCHEMBL15105021 0.72 TRPA1 (0.63) TRPA1RAB9ALTA4HALDH1A1MEN1
SCHEMBL3869325 0.72 TRPA1 (0.63) TRPA1RAB9ALTA4HALDH1A1MEN1
SCHEMBL699621 0.72 TRPA1 (1.00) TRPA1RAB9AALDH1A1CYP1B1NFE2L2
SCHEMBL8845585 0.72 TRPA1 (1.00) TRPA1RAB9AALDH1A1CYP1B1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6097141-A Display device with photoconductive coating SAMSUNG DISPLAY DEVICES CO., LTD. (KR) 2000-08-01 US disclosed
US-5989766-A Photoconductive composition and display adopting photoconductive layer made thereof SAMSUNG DISPLAY DEVICES CO., LTD. (KR) 1999-11-23 US disclosed