SCHEMBL8023490

SCHEMBL8023490

COc1ccc(C#CC=Cc2ccccc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.59
ALDH1A1 P00352 5/20 0.46
MAPT P10636 3/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
CYP1B1 Q16678 2/20 0.46
PPARG P37231 1/20 0.46
NFE2L2 Q16236 1/20 0.46
HSPD1 P10809 1/20 0.46
TNFRSF1A P19438 1/20 0.46
MAOB P27338 1/20 0.46
HSPE1 P61604 1/20 0.46
CYP3A4 P08684 4/20 0.45
RELA Q04206 3/20 0.45
APP P05067 2/20 0.44
CYP1A1 P04798 1/20 0.44
CYP1A2 P05177 1/20 0.44
LMNA P02545 2/20 0.43
EGFR P00533 1/20 0.43
MMP1 P03956 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8023488 1.00 TRPA1 (0.59) TRPA1ALDH1A1MAPTMEN1KMT2A
SCHEMBL3888883 0.82 APP (0.48) TRPA1ALDH1A1MAPTMEN1KMT2A
SCHEMBL3888887 0.82 APP (0.48) TRPA1ALDH1A1MAPTMEN1KMT2A
SCHEMBL8023494 0.80 TRPA1 (0.54) TRPA1ALDH1A1MAPTMEN1KMT2A
SCHEMBL3023009 0.77 TSHR (0.50) ALDH1A1MAPTMEN1KMT2ACYP1B1
SCHEMBL3023006 0.77 TSHR (0.50) ALDH1A1MAPTMEN1KMT2ACYP1B1
SCHEMBL28289709 0.76 TRPA1 (0.54) TRPA1ALDH1A1MAPTMEN1KMT2A
SCHEMBL28289707 0.76 TRPA1 (0.54) TRPA1ALDH1A1MAPTMEN1KMT2A
SCHEMBL13247235 0.76 RELA (0.63) TRPA1ALDH1A1MAPTCYP1B1NFE2L2
SCHEMBL699620 0.76 TRPA1 (1.00) TRPA1ALDH1A1CYP1B1NFE2L2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6097141-A Display device with photoconductive coating SAMSUNG DISPLAY DEVICES CO., LTD. (KR) 2000-08-01 US disclosed
US-5989766-A Photoconductive composition and display adopting photoconductive layer made thereof SAMSUNG DISPLAY DEVICES CO., LTD. (KR) 1999-11-23 US disclosed