Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | ACACA | Q13085 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MPI | P34949 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | RARA | P10276 | 1/20 | 0.30 |
| ▸ | RARB | P10826 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL81022 | 0.93 | PDK2 (0.36) | CYP11B1ALDH1A1HPGDTSHRMAPK1 | |
| SCHEMBL10036758 | 0.91 | CYP11B1 (0.38) | CYP11B1ALDH1A1HPGDTSHRMAPK1 | |
| SCHEMBL10036757 | 0.91 | PDK2 (0.39) | ACACAALDH1A1HPGDCASP1HSD17B10 | |
| SCHEMBL81926 | 0.86 | CYP11B1 (0.38) | CYP11B1ALDH1A1HPGDTSHRMAPK1 | |
| SCHEMBL81159 | 0.82 | PDK2 (0.39) | — | |
| SCHEMBL81053 | 0.82 | PDK2 (0.39) | — | |
| SCHEMBL81461 | 0.82 | PDK2 (0.39) | — | |
| SCHEMBL10036759 | 0.80 | KMT2A (0.34) | ALDH1A1HPGDMAPK1HSD17B10KDM4E | |
| SCHEMBL80224 | 0.79 | ALDH1A1 (0.36) | CYP11B1ALDH1A1HPGDTSHRMAPK1 | |
| SCHEMBL81689 | 0.79 | RARA (0.33) | ALDH1A1HPGDMAPK1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129899-B1 | Azafluorene derivative and organic light-emitting device using the derivative | CANON KABUSHIKI KAISHA (JP) | 2012-03-06 | — | — | US | disclosed |
| US-8129899-B1 | Azafluorene derivative and organic light-emitting device using the derivative | CANON KABUSHIKI KAISHA (JP) | 2012-03-06 | — | — | US | disclosed |