Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL80236 | 0.93 | CYP11B1 (0.39) | CYP11B1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10036757 | 0.87 | PDK2 (0.39) | PDK2PTPN1ADORA1ALOX5APFEN1 | |
| SCHEMBL10036758 | 0.85 | CYP11B1 (0.38) | CYP11B1ALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL81926 | 0.83 | CYP11B1 (0.38) | CYP11B1ALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL81053 | 0.79 | PDK2 (0.39) | PDK2ENPP3 | |
| SCHEMBL81159 | 0.79 | PDK2 (0.39) | PDK2ENPP3 | |
| SCHEMBL81461 | 0.79 | PDK2 (0.39) | PDK2ENPP3 | |
| SCHEMBL10036759 | 0.77 | KMT2A (0.34) | PDK2KDM4EENPP3ALDH1A1HPGD | |
| SCHEMBL80224 | 0.76 | ALDH1A1 (0.36) | CYP11B1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL81689 | 0.76 | RARA (0.33) | PDK2KDM4EENPP3ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129899-B1 | Azafluorene derivative and organic light-emitting device using the derivative | CANON KABUSHIKI KAISHA (JP) | 2012-03-06 | — | — | US | disclosed |
| US-20120049176-A1 | AZAFLUORENE DERIVATIVE AND ORGANIC LIGHT-EMITTING DEVICE USING THE DERIVATIVE | CANON KABUSHIKI KAISHA (JP) | 2012-03-01 | — | — | US | disclosed |