Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 4/20 | 0.38 |
| ▸ | CES1 | P23141 | 4/20 | 0.38 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | PRKCG | P05129 | 1/20 | 0.38 |
| ▸ | PRKCB | P05771 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9426392 | 1.00 | CES2 (0.42) | CES2HSD17B10GMNNTP53POLB | |
| SCHEMBL11474183 | 0.98 | ALDH1A1 (0.42) | CES2HSD17B10GMNNTP53POLB | |
| SCHEMBL8019833 | 0.92 | ALDH1A1 (0.46) | CES2HSD17B10GMNNTP53POLB | |
| SCHEMBL8009891 | 0.92 | ALDH1A1 (0.46) | CES2HSD17B10GMNNTP53POLB | |
| SCHEMBL11464256 | 0.92 | ALDH1A1 (0.39) | CES2HSD17B10GMNNTP53POLB | |
| SCHEMBL948108 | 0.89 | TSHR (0.50) | CES2HSD17B10GMNNTP53POLB | |
| SCHEMBL11544048 | 0.89 | TDP1 (0.36) | HSD17B10TP53ALDH1A1TSHR | |
| SCHEMBL7483245 | 0.89 | TSHR (0.50) | CES2HSD17B10GMNNTP53POLB | |
| SCHEMBL19627041 | 0.89 | TSHR (0.50) | CES2HSD17B10GMNNTP53POLB | |
| SCHEMBL31357726 | 0.89 | TSHR (0.50) | CES2HSD17B10GMNNTP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975714-A2 | LUBRICATING COMPOSTION | Infineum USA L.P. (US) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998039400-A2 | LUBRICATING COMPOSTION | EXXON CHEMICAL PATENTS INC. (US) | 1998-09-11 | — | — | WO | disclosed |
| US-5326487-A | Mixed phosphorous- and sulfur- containing reaction products useful in power transmitting compositions | EXXON CHEMICAL PATENTS INC. (US) | 1994-07-05 | — | — | US | disclosed |