Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 13/20 | 0.63 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.58 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.58 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | DRD4 | P21917 | 2/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6261371 | 0.82 | SIGMAR1 (0.65) | L3MBTL1SIGMAR1SLC6A12TMEM97MCHR1 | |
| SCHEMBL17294724 | 0.79 | SIGMAR1 (0.65) | SIGMAR1SLC6A12TMEM97MCHR1KMT2A | |
| SCHEMBL17294721 | 0.79 | SIGMAR1 (0.65) | SIGMAR1SLC6A12TMEM97MCHR1KMT2A | |
| SCHEMBL17294718 | 0.79 | SIGMAR1 (0.65) | SIGMAR1SLC6A12TMEM97MCHR1KMT2A | |
| SCHEMBL3306841 | 0.79 | SIGMAR1 (0.68) | SIGMAR1KMT2ADRD4DRD2DRD3 | |
| SCHEMBL16828026 | 0.78 | KMT2A (0.79) | L3MBTL1SIGMAR1SLC6A12TMEM97MCHR1 | |
| SCHEMBL8023923 | 0.77 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL2425554 | 0.77 | SIGMAR1 (0.78) | L3MBTL1SIGMAR1SLC6A12TMEM97MCHR1 | |
| SCHEMBL4848461 | 0.77 | SIGMAR1 (0.65) | SIGMAR1KMT2ADRD4DRD2DRD3 | |
| SCHEMBL29712058 | 0.77 | SIGMAR1 (0.65) | SIGMAR1KMT2ADRD4DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000071171-A2 | SIGMA-1 LIGANDS FOR DETERMINING CARCINOMA PROLIFERATIVE STATUS | WAKE FOREST UNIVERSITY (US) | 2000-11-30 | — | — | WO | claimed |
| WO-2000071171-A2 | SIGMA-1 LIGANDS FOR DETERMINING CARCINOMA PROLIFERATIVE STATUS | WAKE FOREST UNIVERSITY (US) | 2000-11-30 | — | — | WO | disclosed |