SCHEMBL8023942

SCHEMBL8023942

Oc1cccc(C2CC(C3CC3)=NN2)c1

nearest known ligand 0.58

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.42
CHRNB4 P30926 1/20 0.39
CHRNA3 P32297 1/20 0.39
OPRL1 P41146 1/20 0.38
DRD2 P14416 4/20 0.38
DRD3 P35462 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9135199 0.75 MAOB (0.51) CA1
SCHEMBL8024272 0.75 MAOA (0.54) CA1
SCHEMBL29427014 0.72 DRD2 (0.59) OPRL1DRD2DRD3
SCHEMBL1608042 0.72 DRD2 (0.59) OPRL1DRD2DRD3
SCHEMBL9379642 0.68 DRD2 (0.40) CA1CHRNB4CHRNA3DRD2DRD3
Cyanide SCHEMBL27730527 0.68 DRD2 (0.54) OPRL1DRD2DRD3
SCHEMBL8870493 0.67 CHRNB4 (0.49) CHRNB4CHRNA3DRD2DRD3
SCHEMBL24736158 0.66 ESR2 (0.59) OPRL1DRD2DRD3
SCHEMBL4280772 0.66 CHRNB2 (0.53) CHRNB4CHRNA3DRD2DRD3
SCHEMBL1658753 0.65 HDAC4 (0.56) DRD2DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1113859-C Substituted cyclopropyl phenoxymethyl phenyl carbamates and their use as fungicides DOW INO CO LTD (US) 2003-07-09 CN disclosed
US-6114375-A FOR CONTROLLING PHYTOPATHOGENIC FUNGI; METHYL N-ALKOXY-N-(2-((SUBSTITUTED CYCLOPROPYL)PHENOXYMETHYL)PHENYL) CARBAMATE DERIVATIVES ROHM AND HAAS COMPANY (US) 2000-09-05 US disclosed
US-6022891-A Substituted cyclopropyl phenoxymethyl phenyl carbamates and their use as fungicides ROHM AND HAAS COMPANY (US) 2000-02-08 US disclosed
CN-1226552-A Substituted cyclopropyl phenoxymethyl phenyl carbamates and their use as fungicides ROHM & HAAS (US) 1999-08-25 CN disclosed
EP-0924197-A1 Substituted cyclopropyl phenoxymethyl phenyl carbamates and their use as fungicides ROHM AND HAAS COMPANY (US) 1999-06-23 EP disclosed