SCHEMBL3799748

SCHEMBL3799748

CC(C)(C)[Si](C)(C)OCc1ccc(C2=C(c3ccccc3)C(O)(c3ccccc3)C(c3ccc(CO[Si](C)(C)C(C)(C)C)cc3)C2=O)cc1

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CRHBP P24387 1/20 0.37
CRHR2 Q13324 1/20 0.37
NAAA Q02083 4/20 0.32
TOP2A P11388 1/20 0.32
EDNRA P25101 1/20 0.31
PREP P48147 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
TACR1 P25103 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13191513 0.84 CRHBP (0.41) CRHBPCRHR2NAAAEDNRAMAPT
SCHEMBL13170498 0.81 CRHBP (0.44) CRHBPCRHR2EDNRA
SCHEMBL3799755 0.77 CRHBP (0.35) CRHBPCRHR2TOP2AMAPTHPGD
SCHEMBL8017542 0.77 CRHBP (0.50) CRHBPCRHR2MAPT
SCHEMBL8017540 0.77 CRHBP (0.50) CRHBPCRHR2MAPT
SCHEMBL8023972 0.77 CRHBP (0.50) CRHBPCRHR2MAPT
SCHEMBL8017544 0.77 CRHBP (0.50) CRHBPCRHR2MAPT
SCHEMBL3799785 0.73 PREP (0.43) NAAAPREPTACR1
SCHEMBL3796502 0.68 IDO1 (0.39) NAAAPREPTACR1
SCHEMBL1315036 0.66 IDO1 (0.46) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100222432-A1 Synthetic Carbon Nanotubes KANSAS STATE UNIVERSITY RESEARCH FOUNDATION 2010-09-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100222432-A1 Synthetic Carbon Nanotubes CYCS, CHN2, TUBA3C CRHBP 1545/4885CRHR2 2699/4885NAAA 3128/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.