Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 4/20 | 0.38 |
| ▸ | RARA | P10276 | 2/20 | 0.38 |
| ▸ | RARG | P13631 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27243408 | 0.93 | CNR2 (0.35) | MEN1KMT2AGAAPOLBGFER | |
| SCHEMBL8766363 | 0.86 | MEN1 (0.43) | MEN1KMT2AGAAPOLBGFER | |
| SCHEMBL2420330 | 0.81 | MEN1 (0.50) | MEN1KMT2AGAAPOLBGFER | |
| SCHEMBL27419643 | 0.79 | CNR2 (0.48) | MEN1KMT2AGAAPOLBGFER | |
| SCHEMBL5028672 | 0.79 | KMT2A (0.43) | MEN1KMT2AGAAPOLBGFER | |
| SCHEMBL3755595 | 0.78 | MEN1 (0.55) | MEN1KMT2AGAAPOLBGFER | |
| SCHEMBL6033366 | 0.75 | MEN1 (0.47) | MEN1KMT2AGAAPOLBGFER | |
| SCHEMBL27829414 | 0.75 | MEN1 (0.46) | MEN1KMT2AGAAPOLBGFER | |
| Formic Acid SCHEMBL28092830 | 0.75 | RARB (0.44) | MEN1KMT2AGAAPOLBGFER | |
| SCHEMBL30179543 | 0.74 | MEN1 (0.40) | MEN1KMT2AGAAPOLBGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986537-A2 | NOVEL HETEROETHYNYLENE COMPOUNDS AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | Galderma Research & Development, S.N.C. (FR) | 2000-03-22 | — | — | EP | disclosed |
| WO-1999050239-A2 | NOVEL HETEROETHYNYLENE COMPOUNDS AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 1999-10-07 | — | — | WO | disclosed |
| EP-0358574-B1 | PROCESS FOR THE PREPARATION OF ADAMANTANE-1 DERIVATIVES | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA (FR) | 1993-02-17 | — | — | EP | disclosed |
| EP-0358574-A1 | Process for the preparation of adamantane-1 derivatives | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA (FR) | 1990-03-14 | — | — | EP | disclosed |