SCHEMBL27419643

SCHEMBL27419643

Cc1cc(O)ccc1C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.69

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 2/20 0.48
POLB P06746 2/20 0.43
MEN1 O00255 1/20 0.43
GAA P10253 1/20 0.43
GFER P55789 1/20 0.43
KMT2A Q03164 1/20 0.43
RARB P10826 3/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
ALOX12 P18054 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
GPR55 Q9Y2T6 1/20 0.39
HSP90AA1 P07900 1/20 0.38
NPC1 O15118 1/20 0.38
RARA P10276 2/20 0.38
RARG P13631 2/20 0.38
EPHX2 P34913 1/20 0.37
IKBKB O14920 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2087563 0.90 CNR2 (0.43) CNR2POLBMEN1GAAGFER
SCHEMBL2420330 0.81 MEN1 (0.50) CNR2POLBMEN1GAAGFER
SCHEMBL8024133 0.79 MEN1 (0.43) CNR2POLBMEN1GAAGFER
SCHEMBL549416 0.79 MEN1 (0.40) CNR2POLBMEN1GAAGFER
SCHEMBL26272370 0.79 MEN1 (0.36) CNR2POLBMEN1GAAGFER
SCHEMBL5028672 0.79 KMT2A (0.43) CNR2POLBMEN1GAAGFER
SCHEMBL3755595 0.78 MEN1 (0.55) CNR2POLBMEN1GAAGFER
SCHEMBL548545 0.77 NPC1 (0.41) CNR2POLBMEN1GAAGFER
SCHEMBL549467 0.77 MEN1 (0.39) CNR2POLBMEN1GAAGFER
SCHEMBL27449138 0.77 MEN1 (0.44) CNR2POLBMEN1GAAGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121378037-A Synthesis and anti-tumor activity research of 4-adamantyl 3-methylphenol derivative 长春工业大学 2026-01-23 CN disclosed
CN-101547885-A Adamantane derivative, process for producing the same, and resin composition containing adamantane derivative IDEMITSU KOSAN CO (JP) 2009-09-30 CN disclosed
CN-1117966-A Biphenyl derivatives EISAI CO LTD (JP) 1996-03-06 CN disclosed