Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 5/20 | 0.39 |
| ▸ | HMGCR | P04035 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 4/20 | 0.33 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2043689 | 0.98 | PTPN7 (0.42) | LMNAPTPN7HMGCRRECQLTDP1 | |
| SCHEMBL9548439 | 0.98 | PTPN7 (0.42) | LMNAPTPN7HMGCRRECQLTDP1 | |
| SCHEMBL23034432 | 0.81 | LMNA (0.41) | LMNAPTPN7HMGCRRECQLTDP1 | |
| SCHEMBL25735589 | 0.79 | PTPN7 (0.39) | LMNAPTPN7HMGCRRECQLTDP1 | |
| SCHEMBL15506096 | 0.79 | PTPN7 (0.39) | LMNAPTPN7HMGCRRECQLTDP1 | |
| SCHEMBL23015071 | 0.79 | LMNA (0.32) | LMNA | |
| SCHEMBL23014741 | 0.78 | CES1 (0.36) | LMNAFAAHCES1CES2 | |
| SCHEMBL23014991 | 0.78 | CES2 (0.37) | LMNAMEN1USP2MAPTKMT2A | |
| SCHEMBL28926115 | 0.75 | LMNA (0.44) | LMNAPTPN7HMGCRRECQLTDP1 | |
| SCHEMBL23034420 | 0.75 | LMNA (0.44) | LMNAPTPN7HMGCRRECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815066-B1 | NOVEL INTERMEDIATES FOR THE SYNTHESIS OF TRIFLUOROMETHYLATED ORGANIC COMPOUNDS | ALLIED SIGNAL INC (US) | 2000-01-05 | — | — | EP | disclosed |
| WO-1999037610-A1 | NOVEL CHEMICAL INTERMEDIATES BEARING A TRIFLUOROMETHYL GROUP | ALLIEDSIGNAL INC. (US) | 1999-07-29 | — | — | WO | disclosed |
| EP-0815066-A1 | NOVEL INTERMEDIATES FOR THE SYNTHESIS OF TRIFLUOROMETHYLATED ORGANIC COMPOUNDS | AlliedSignal Inc. (US) | 1998-01-07 | — | — | EP | disclosed |
| US-5654473-A | Intermediates for the synthesis of trifluoromethylated organic compounds | ALLIEDSIGNAL INC. (US) | 1997-08-05 | — | — | US | disclosed |
| WO-1996028404-A1 | NOVEL INTERMEDIATES FOR THE SYNTHESIS OF TRIFLUOROMETHYLATED ORGANIC COMPOUNDS | ALLIEDSIGNAL INC. (US) | 1996-09-19 | — | — | WO | disclosed |